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SELPLG antibody

SELPLG Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7235475
  • Target See all SELPLG Antibodies
    SELPLG (Selectin P Ligand (SELPLG))
    Reactivity
    • 74
    • 35
    • 21
    • 1
    • 1
    • 1
    Human
    Host
    • 67
    • 28
    • 14
    Rabbit
    Clonality
    • 65
    • 43
    • 1
    Polyclonal
    Conjugate
    • 39
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SELPLG antibody is un-conjugated
    Application
    • 71
    • 69
    • 24
    • 18
    • 16
    • 9
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human SELPLG
    Isotype
    IgG
    Top Product
    Discover our top product SELPLG Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.4 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SELPLG (Selectin P Ligand (SELPLG))
    Alternative Name
    SELPLG (SELPLG Products)
    Synonyms
    CD162 antibody, CLA antibody, PSGL-1 antibody, PSGL1 antibody, SELPLG antibody, SELPG antibody, Psgl-1 antibody, Psgl1 antibody, Selp1 antibody, Selpl antibody, selectin P ligand antibody, selectin, platelet (p-selectin) ligand antibody, clasper antibody, SELPLG antibody, Selplg antibody, cla antibody
    Background
    This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
    UniProt
    Q14242
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