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anti-Sphingomyelin Synthase 1 (SGMS1) Antibodies

The protein encoded by SGMS1 is predicted to be a five-pass transmembrane protein. Additionally we are shipping Sphingomyelin Synthase 1 Kits (9) and Sphingomyelin Synthase 1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SGMS1 259230 Q86VZ5
SGMS1 208449 Q8VCQ6
SGMS1 353229 Q7TSX5
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Top anti-Sphingomyelin Synthase 1 Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SGMS1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB SGMS1 Antibody (N-term) (ABIN657485) western blot analysis in MCF-7 cell line lysates (35 µg/lane). This demonstrates the SGMS1 antibody detected the SGMS1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (fro), WB 10 blots Log in to see 6 to 8 Days
$533.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Sgms1 AntibodyTitration: 1.0 µg/mL  Positive Control: Mouse Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse brain labeled with Anti-Sphingomyelin Synthase 1 Polyclonal Antibody, Unconjugated (ABIN705371) followed by conjugation to the secondary antibody and DAB staining Lane 1: mouse embryo lysates Lane 2: mouse heart lysates probed with Anti Sphingomyelin Synthase 1 Polyclonal Antibody, Unconjugated (ABIN705371) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 49kD. Observed band size: 49kD. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB SGMS1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$533.50
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$533.50
Details

SGMS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Sphingomyelin Synthase 1 Antibodies

  1. Human Polyclonal Sphingomyelin Synthase 1 Primary Antibody for IHC (p), WB - ABIN657485 : Wang, Yang, Tangchaiburana, Ndeh, Markham, Tsegaye, Dunn, Wang, Bellizzi, Parsons, Morrissey, Bravo, Lynch, Xiao: An inositolphosphorylceramide synthase is involved in regulation of plant programmed cell death associated with defense in Arabidopsis. in The Plant cell 2009 (PubMed)
    Show all 2 references for ABIN657485

  2. Human Polyclonal Sphingomyelin Synthase 1 Primary Antibody for EIA, WB - ABIN265114 : Huitema, van den Dikkenberg, Brouwers, Holthuis: Identification of a family of animal sphingomyelin synthases. in The EMBO journal 2004 (PubMed)

  3. Chicken Polyclonal Sphingomyelin Synthase 1 Primary Antibody for WB - ABIN2774110 : Ding, Li, Hailemariam, Mukherjee, Maxfield, Wu, Jiang: SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis. in Journal of lipid research 2008 (PubMed)

More Antibodies against Sphingomyelin Synthase 1 Interaction Partners

Human Sphingomyelin Synthase 1 (SGMS1) interaction partners

  1. A study of the expression of the full-length SMS1 protein and the sum of the alternative transcripts encoding this protein in human tissues.

  2. The structural organization of 5'-UTR (show UTS2R Antibodies) variants of SGMS1 transcripts, directed by alternative promoters, is substantially different; this can provide regulation of the gene functioning on post-transcriptional level.

  3. We found upregulation of specific sphingolipid enzymes, namely sphingomyelin synthase 1 (SMS1), sphingomyelinase 3 (SMPD3 (show SMPD3 Antibodies)), and glucosylceramide synthase (GCS (show UGCG Antibodies)) in the endometrium of endometriotic women.

  4. SGMS activity impacts on amyloid precursor protein (show APP Antibodies) processing to produce amyloid-beta (Abeta (show APP Antibodies)) and it could be a contributing factor in Abeta (show APP Antibodies) pathology associated with Alzheimer's disease.

  5. The amount of SMS1 transcripts varies considerably between different human tissues.

  6. Findings indicate that Sms1 is a downstream target of Bcr-abl (show ABL1 Antibodies), involved in sustaining cell proliferation of Bcr-abl (show ABL1 Antibodies)-positive cells.

  7. SMS1 and SMS2 (show SGMS2 Antibodies) are capable of regulating TGN (show TG Antibodies)-mediated protein trafficking and secretion

  8. Data indicate that the increased sphingomyelin mass was due to a rapid and highly specific activation of sphingomyelin synthases SMS1 and SMS2 (show SGMS2 Antibodies).

  9. SMS1-mediated SM synthesis directs Tf-TfR to undergo clathrin-dependent endocytosis and recycling, promoting the proliferation of lymphoma cells.

  10. Our results indicate that the regulation of SMS1 expression is complex and occurs at the transcriptional, post-transcriptional and translational levels.

Mouse (Murine) Sphingomyelin Synthase 1 (SGMS1) interaction partners

  1. Sphingomyelin synthase 1 regulates Neuro-2a cell proliferation and cell cycle progression through modulation of p27 (show CDKN1B Antibodies) expression and Akt (show AKT1 Antibodies) signaling

  2. study reveals that all mouse SMS family members (SMSr, SMS1, and SMS2) have CPE synthase activity

  3. that SMS1 is crucial to control oxidative stress in order to maintain white adipose tissue function.

  4. Defects in the stria vascularis with reductions in endocochlear potentials together with hair cell dysfunction may account, at least partially, for hearing impairments in SMS1-/- mice.

  5. The deficiency of membrane sphingomyelin caused the CD4 (show CD4 Antibodies) T-cell dysfunction through impaired lipid raft function contributing to protection of ConA-induced liver injury, and suggesting that the membrane sphingomyelin is critical for full T-cell activation.

  6. Sms1 deficiency decreases sphingomyelin, but dramatically increases the levels of glycosphingolipids. Atherosclerosis in Sms1(-/-)-->Ldlr (show LDLR Antibodies)(-/-) mice is significantly decreased.

  7. SMS1 and SMS2 (show SGMS2 Antibodies) play distinct roles in regulating local sphingomyelin clustering.

  8. SMS1-mediated SM synthesis directs Tf-TfR to undergo clathrin-dependent endocytosis and recycling, promoting the proliferation of lymphoma cells.

  9. SMS1 is important for controlling ROS (show ROS1 Antibodies) generation, and SMS1 is required for normal mitochondrial function and insulin (show INS Antibodies) secretion in pancreatic beta-cells

Sphingomyelin Synthase 1 (SGMS1) Antigen Profile

Protein Summary

The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain.

Gene names and symbols associated with SGMS1

  • sphingomyelin synthase 1 (SGMS1) antibody
  • sphingomyelin synthase 1 (sgms1) antibody
  • sphingomyelin synthase 1 (Sgms1) antibody
  • 9530058O11Rik antibody
  • AI841905 antibody
  • C80702 antibody
  • hmob33 antibody
  • MGC81436 antibody
  • Mob antibody
  • MOB1 antibody
  • Sms1 antibody
  • Sor1 antibody
  • Tmem23 antibody

Protein level used designations for SGMS1

phosphatidylcholine:ceramide cholinephosphotransferase 1 , sphingomyelin synthase 1 , phosphatidylcholine:ceramide cholinephosphotransferase 1-like , medulla oblongata-derived protein , protein Mob , transmembrane protein 23 , mob-1

GENE ID SPECIES
100062484 Equus caballus
414566 Xenopus laevis
450460 Pan troglodytes
704027 Macaca mulatta
100013212 Monodelphis domestica
100444992 Pongo abelii
100601656 Nomascus leucogenys
259230 Homo sapiens
208449 Mus musculus
378907 Gallus gallus
477582 Canis lupus familiaris
100037303 Sus scrofa
533538 Bos taurus
353229 Rattus norvegicus
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