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The protein encoded by SGMS1 is predicted to be a five-pass transmembrane protein. Additionally we are shipping Sphingomyelin Synthase 1 Kits (9) and Sphingomyelin Synthase 1 Proteins (3) and many more products for this protein.
Showing 10 out of 55 products:
Human Polyclonal Sphingomyelin Synthase 1 Primary Antibody for IHC (p), WB - ABIN657485
Wang, Yang, Tangchaiburana, Ndeh, Markham, Tsegaye, Dunn, Wang, Bellizzi, Parsons, Morrissey, Bravo, Lynch, Xiao: An inositolphosphorylceramide synthase is involved in regulation of plant programmed cell death associated with defense in Arabidopsis. in The Plant cell 2009
Show all 2 references for ABIN657485
Human Polyclonal Sphingomyelin Synthase 1 Primary Antibody for EIA, WB - ABIN265115
Huitema, van den Dikkenberg, Brouwers, Holthuis: Identification of a family of animal sphingomyelin synthases. in The EMBO journal 2004
Chicken Polyclonal Sphingomyelin Synthase 1 Primary Antibody for WB - ABIN2774110
Ding, Li, Hailemariam, Mukherjee, Maxfield, Wu, Jiang: SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis. in Journal of lipid research 2008
A study of the expression of the full-length SMS1 protein and the sum of the alternative transcripts encoding this protein in human tissues.
The structural organization of 5'-UTR (show UTS2R Antibodies) variants of SGMS1 transcripts, directed by alternative promoters, is substantially different; this can provide regulation of the gene functioning on post-transcriptional level.
We found upregulation of specific sphingolipid enzymes, namely sphingomyelin synthase 1 (SMS1), sphingomyelinase 3 (SMPD3 (show SMPD3 Antibodies)), and glucosylceramide synthase (GCS (show UGCG Antibodies)) in the endometrium of endometriotic women.
SGMS activity impacts on amyloid precursor protein (show APP Antibodies) processing to produce amyloid-beta (Abeta (show APP Antibodies)) and it could be a contributing factor in Abeta (show APP Antibodies) pathology associated with Alzheimer's disease.
The amount of SMS1 transcripts varies considerably between different human tissues.
Findings indicate that Sms1 is a downstream target of Bcr-abl (show ABL1 Antibodies), involved in sustaining cell proliferation of Bcr-abl (show ABL1 Antibodies)-positive cells.
SMS1 and SMS2 (show SGMS2 Antibodies) are capable of regulating TGN (show TG Antibodies)-mediated protein trafficking and secretion
Data indicate that the increased sphingomyelin mass was due to a rapid and highly specific activation of sphingomyelin synthases SMS1 and SMS2 (show SGMS2 Antibodies).
SMS1-mediated SM synthesis directs Tf-TfR to undergo clathrin-dependent endocytosis and recycling, promoting the proliferation of lymphoma cells.
Our results indicate that the regulation of SMS1 expression is complex and occurs at the transcriptional, post-transcriptional and translational levels.
Sphingomyelin synthase 1 regulates Neuro-2a cell proliferation and cell cycle progression through modulation of p27 (show CDKN1B Antibodies) expression and Akt (show AKT1 Antibodies) signaling
study reveals that all mouse SMS family members (SMSr, SMS1, and SMS2) have CPE synthase activity
that SMS1 is crucial to control oxidative stress in order to maintain white adipose tissue function.
Defects in the stria vascularis with reductions in endocochlear potentials together with hair cell dysfunction may account, at least partially, for hearing impairments in SMS1-/- mice.
The deficiency of membrane sphingomyelin caused the CD4 (show CD4 Antibodies) T-cell dysfunction through impaired lipid raft function contributing to protection of ConA-induced liver injury, and suggesting that the membrane sphingomyelin is critical for full T-cell activation.
Sms1 deficiency decreases sphingomyelin, but dramatically increases the levels of glycosphingolipids. Atherosclerosis in Sms1(-/-)-->Ldlr (show LDLR Antibodies)(-/-) mice is significantly decreased.
SMS1 and SMS2 (show SGMS2 Antibodies) play distinct roles in regulating local sphingomyelin clustering.
SMS1 is important for controlling ROS (show ROS1 Antibodies) generation, and SMS1 is required for normal mitochondrial function and insulin (show INS Antibodies) secretion in pancreatic beta-cells
The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain.
phosphatidylcholine:ceramide cholinephosphotransferase 1
, sphingomyelin synthase 1
, phosphatidylcholine:ceramide cholinephosphotransferase 1-like
, medulla oblongata-derived protein
, protein Mob
, transmembrane protein 23