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anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Antibodies

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. Additionally we are shipping Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Proteins (11) and Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SDHB 6390 P21912
SDHB 67680 Q9CQA3
SDHB 298596 P21913
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Top anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Antibodies at antibodies-online.com

Showing 10 out of 110 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SDHB Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185447 (0.03µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB SDHB Antibody (C-term) (ABIN1881781) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the SDHB antibody detected the SDHB protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB Human Heart (formalin-fixed, paraffin-embedded) stained with SDHBat 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Antibody (0.03 µg/ml) staining of Human Liver lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-SDHB antibody, Western blotting All lanes: Anti SDHB  at 0.5ug/ml Lane 1: Rat Testis Tissue Lysate at 50ug Lane 2: Rat Cardiac Muscle Tissue Lysate at 50ug Lane 3: Jurkat Whole Cell Lysate at 40ug Predicted bind size: 32KD Observed bind size: 32KD Anti-SDHB antibody, IHC(P) IHC(P): Rat Cardiac Muscle Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image SDHB antibody [C2C3], C-term detects SDHB protein by Western blot analysis. A. 30 µg Neuro2A whole cell lysate/extract 12 % SDS-PAGE SDHB antibody [C2C3], C-term , dilution: 1:1000 IHC-P Image SDHB antibody [C2C3], C-term detects SDHB protein at mitochindria on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human colon carcinoma. SDHB antibody [C2C3], C-term , diluted at 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Sdhb AntibodyTitration: 1.0 µg/mL  Positive Control: Mouse Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Heart (formalin-fixed, paraffin-embedded) stained with SDHB antibody ABIN364266 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details

SDHB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Antibodies

  1. Human Polyclonal SDHB Primary Antibody for WB - ABIN1881781 : Cerecer-Gil, Figuera, Llamas, Lara, Escamilla, Ramos, Estrada, Hussain, Gaal, Korpershoek, de Krijger, Dinjens, Devilee, Bayley: Mutation of SDHB is a cause of hypoxia-related high-altitude paraganglioma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2010 (PubMed)
    Show all 4 references for ABIN1881781

  2. Cow (Bovine) Polyclonal SDHB Primary Antibody for WB - ABIN2783181 : Cascón, Landa, López-Jiménez, Díez-Hernández, Buchta, Montero-Conde, Leskelä, Leandro-García, Letón, Rodríguez-Antona, Eng, Neumann, Robledo: Molecular characterisation of a common SDHB deletion in paraganglioma patients. in Journal of medical genetics 2008 (PubMed)
    Show all 2 references for ABIN2783181

  3. Human Polyclonal SDHB Primary Antibody for ELISA, WB - ABIN185447 : Selak, Armour, MacKenzie, Boulahbel, Watson, Mansfield, Pan, Simon, Thompson, Gottlieb: Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. in Cancer cell 2005 (PubMed)
    Show all 2 references for ABIN185447

More Antibodies against Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Interaction Partners

Fruit Fly (Drosophila melanogaster) Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. sdhB mutant is hypersensitive to oxygen and displays hallmarks of a progeroid syndrome

Human Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. The low penetrance of SDHB mutations may obscure the hereditary nature of SDHB-linked disease and is important in the counseling of SDHB-linked patients.

  2. Succinate dehydrogenase (show SDHA Antibodies) deficiency is a rare leukoencephalopathy, for which improved recognition by magnetic resonance imaging (MRI (show C7ORF49 Antibodies)) in combination with advanced sequencing technologies allows noninvasive diagnostic confirmation.

  3. 15 YEARS OF PARAGANGLIOMA: Genetics and mechanism of pheochromocytoma-paraganglioma syndromes characterized by germline SDHB and SDHD (show SDHD Antibodies) mutations

  4. Study reveals new insights into the effects of SDHB mutations and the power of structural modelling in predicting biological consequences.

  5. for the first time, we show a high correlation between urinary bladder paragangliomas and SDHB mutations

  6. Findings provide a conceptual framework for understanding how particular mutations disproportionately cause the loss of SDH (show SARDH Antibodies) activity, resulting in accumulation of succinate and metabolic remodeling in SDHB cancer syndromes.

  7. Germline mutation in the SDHB gene is the only reliable predictor of malignant Paragangliomas.

  8. Report direct correlation between the presence of an SDHB mutation, whether germline or somatic, and negative SDHB immunohistochemical staining in bladder paragangliomas.

  9. This study strengthens the etiological association of SDH (show SARDH Antibodies) genes with pituitary neoplasia, renal tumorigenesis, and gastric gastrointestinal stromal tumors. Also, pancreatic neuroendocrine tumor falls within the SDH (show SARDH Antibodies)-related tumor spectrum.

  10. SDHB immunohistochemistry alone may be misleading in excluding tumors other than gastrointestinal stromal tumors

Pig (Porcine) Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. tissue expression analysis indicated that that swine SDHB, SNRPA (show SNRPA Antibodies) and CRYBB1 (show CRYBB1 Antibodies) gene were differentially expressed in tissues including fat, lung, muscle, small intestine, kidney, large intestine, spleen and liver

Mouse (Murine) Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. Data show that lack of succinate dehydrogenase (SDH (show SDHA Antibodies)) activity commits cells to consume extracellular pyruvate.

  2. Using Sdhb(+/-) mice, we provide evidence that pituitary hyperplasia in SDHx-deficient cells may be the initial abnormality in the cascade of events leading to pituitary adenoma formation.

  3. Tumor-derived FH and SDH (show SDS Antibodies) mutations accumulate fumarate and succinate, leading to enzymatic inhibition of multiple alpha-KG-dependent dioxygenases and consequent alterations of genome-wide histone and DNA methylation (show HELLS Antibodies).

  4. Data show that two subunits of complex II (succinate dehydrogenase (show SDHD Antibodies), or SDH (show SDS Antibodies)), SDHA (show SDHA Antibodies) and SDHB, interacted specifically with SIRT3 (show SIRT3 Antibodies).

Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Antigen Profile

Protein Summary

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Gene names and symbols associated with SDHB

  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB) antibody
  • succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 (SDH2-3) antibody
  • Succinate dehydrogenase B (SdhB) antibody
  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (sdhb) antibody
  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (Sdhb) antibody
  • 0710008N11Rik antibody
  • CG3283 antibody
  • CWS2 antibody
  • Dmel\\CG3283 antibody
  • fj46d06 antibody
  • IP antibody
  • PGL4 antibody
  • SDH antibody
  • SDH-Ip antibody
  • SDH1 antibody
  • SDH2 antibody
  • sdhB antibody
  • SDHIP antibody
  • succinate dehydrogenase 2-3 antibody
  • wu:fj46d06 antibody

Protein level used designations for SDHB

succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial , succinate dehydrogenase complex subunit B , CG3283-PA , COMPLEX II: iron-sulfur subunit , SdhB-PA , iron-sulfur protein subunit of succinate dehydrogenase , succinate dehydrogenase , succinate dehydrogenase B , succinate dehydrogenase Iron-sulfur , succinate dehydrogenase Iron-sulfur protein , succinate dehydrogenase iron protein , succinate dehydrogenase subunit b , iron-sulfur subunit of complex II , Iron-sulfur subunit of complex II , IP , ip

GENE ID SPECIES
100050091 Equus caballus
770063 Arabidopsis thaliana
35590 Drosophila melanogaster
100144957 Xenopus (Silurana) tropicalis
6390 Homo sapiens
478217 Canis lupus familiaris
414412 Sus scrofa
286840 Bos taurus
100328585 Oryctolagus cuniculus
67680 Mus musculus
298596 Rattus norvegicus
562149 Danio rerio
379939 Xenopus laevis
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