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TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. Additionally we are shipping TBX3 Kits (20) and TBX3 Proteins (13) and many more products for this protein.
Showing 10 out of 94 products:
Human Polyclonal TBX3 Primary Antibody for EIA, WB - ABIN955111
Christoffels, Smits, Kispert, Moorman: Development of the pacemaker tissues of the heart. in Circulation research 2010
Show all 5 references for ABIN955111
Cow (Bovine) Polyclonal TBX3 Primary Antibody for WB - ABIN2777925
Bozyk, Popova, Bentley, Goldsmith, Linn, Weiss, Hershenson: Mesenchymal stromal cells from neonatal tracheal aspirates demonstrate a pattern of lung-specific gene expression. in Stem cells and development 2011
Show all 2 references for ABIN2777925
Cow (Bovine) Polyclonal TBX3 Primary Antibody for IHC, WB - ABIN2777924
Yarosh, Barrientos, Esmailpour, Lin, Carpenter, Osann, Anton-Culver, Huang: TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases. in Cancer research 2008
Human Polyclonal TBX3 Primary Antibody for ELISA, WB - ABIN1451829
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
identified two different TBX3 alleles causing non-dun color. non-dun2 is a recently derived allele, whereas the Dun and non-dun1 TBX3 alleles are found in ancient horse DNA, demonstrating that this polymorphism predates horse domestication
Tbx3 was found to be overexpressed in 46 of 98 human gastric cancer samples
These include a patient with hypoplastic phalanges and absent hallux bilaterally with de novo deletion of 11.9 Mb on 7p21.1-22.1 spanning 63 genes including RAC1, another patient with severe Holt-Oram syndrome and a large de novo deletion 2.2 Mb on 12q24.13-24.21 spanning 20 genes including TBX3 and TBX5 (show TBX5 Antibodies), and a third patient with acheiropodia who had a nullizygous deletion of 102 kb on 7q36.3 spanning LMBR1 (show LMBR1 Antibodies)
this new molecular-grade based on the combination of TBX2 (show TBX2 Antibodies) and TBX3 methylation is an excellent marker for predicting progression to muscle-invasive bladder cancer in patients with primary pTaG1/2 bladder cancer.
Paracrine WNT (show WNT2 Antibodies) signaling is stimulated by estrogen and progesterone, while autocrine WNT (show WNT2 Antibodies) signaling is induced by the embryonic T-box transcription factor TBX3
Overexpression of Tbx3 is associated with pancreatic carcinoma.
Data show that the down-regulation of T-box transcription factor TBX2 (show TBX2 Antibodies) by transforming growth factor beta I (TGF-beta1 (show TGFB1 Antibodies)) is mediated by T-box transcription factor TBX3.
Polymorphisms in several genes involved in the Wnt (show WNT2 Antibodies) signaling pathway were associated with hepatic fibrosis or inflammation risk in HCV-infected males.
TBX3 gene variants may contribute to indirect inguinal hernia as a rare risk factor by reducing TBX3 levels
An enhancement in TBX3 protein expression both in glomerular and tubular regions.
The pleiotropic effects of TBX3 mutations in humans and mice likely result from disrupting at least two molecular functions of this protein: transcriptional regulation and pre-mRNA splicing.
T-box3 interacts with Kif7 (show KIF7 Antibodies) and is required for normal stoichiometry and function of a Kif7 (show KIF7 Antibodies)/Sufu (show SUFUH Antibodies) complex that regulates Gli3 (show GLI3 Antibodies) stability and processing.
Low TBX3 levels are associated with reduced pluripotency for embryonic stem cells, resembling the more mature epiblast.
miR (show MLXIP Antibodies)-93 controls Tbx3 expression, thereby limiting self-renewal in early adipocyte precursors.
In-depth transcriptome analysis of this mESC state reveals Dppa3 (show DPPA3 Antibodies) as a direct downstream target of Tbx3.We show that Tbx3, a downstream target of Wnt (show WNT2 Antibodies) signaling, fine tunes these divergent roles of Wnt (show WNT2 Antibodies) signaling in mESCs
Hoxc8 (show HOXC8 Antibodies) initiates an ectopic mammary program by regulating Fgf10 (show FGF10 Antibodies) and Tbx3 expression and Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling
Tbx3 can activate Zscan4 (show ZSCAN4 Antibodies)(+)/2C state by negative regulation of DNA methylation (show HELLS Antibodies) at repeated sequences, linking to telomere maintenance and self-renewal of ES cells.
Tbx3 is important for the generation of hormone-sensing cells.
Taken together, we define further facets of TBX3 actions and map TBX3 as an upstream regulator of the mesendoderm transcriptional program during gastrulation.
The Tbx3 locus forms a CTCF (show CTCF Antibodies)-independent autonomous regulatory domain with multiple combinatorial regulatory elements that control the precise pattern of Tbx3 in the cardiac conduction system.
Tbx3 plays an important role in osteoclastogenesis at least in part by regulating CSF1 (show CSF1 Antibodies)-dependent expression of JDP2 (show JDP2 Antibodies).
Results suggested that Tbx3 and Nr5alpha2 may have vital roles in pluripotent stem cells.
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms\; however, the full length nature of one variant has not been determined.
, transcription factor Tbx3
, T-box 3 protein
, T-box 3 (ulnar mammary syndrome)
, T-box transcription factor TBX3-like
, t-box transcription factor TBX3-like
, T-box protein 3
, T-box transcription factor TBX3
, bladder cancer related protein XHL
, T-Box protein 3