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TFPI2 encodes a member of the Kunitz-type serine proteinase inhibitor family. Additionally we are shipping TFPI2 Antibodies (115) and TFPI2 Kits (30) and many more products for this protein.
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Human TFPI2 Protein expressed in HEK-293 - ABIN2666517
Lwaleed, Bass: Tissue factor pathway inhibitor: structure, biology and involvement in disease. in The Journal of pathology 2006
Show all 8 references for ABIN2666517
Human TFPI2 Protein expressed in Human Cells - ABIN2003028
Miyagi, Koshikawa, Yasumitsu, Miyagi, Hirahara, Aoki, Misugi, Umeda, Miyazaki: cDNA cloning and mRNA expression of a serine proteinase inhibitor secreted by cancer cells: identification as placental protein 5 and tissue factor pathway inhibitor-2. in Journal of biochemistry 1995
Human TFPI2 Protein expressed in HEK-293 Cells - ABIN2181806
Rao, Liu, Peavey, Woodley: Novel extracellular matrix-associated serine proteinase inhibitors from human skin fibroblasts. in Archives of biochemistry and biophysics 1995
Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 (show PRSS3 Proteins) accumulated tissue factor pathway inhibitor-2 (TFPI-2) in the matrix.
Hypermethylation of TFPI2 promoter is increased in inflamed colon tissue.
DNA methylation of TFPI2 may play an important role in the carcinogenesis of cervical cancer and that the differential methylation of TFPI2 may at least partially explain the disparity in cervical cancer incidence between Uygur and Han women.
our findings suggested that the differential expression of MMP-2 (show MMP2 Proteins) and TFPI-2 have a negative correlation in pancreatic carcinoma
Our finding suggests that the decreased expression of TFPI-2 may play an important role in the carcinogenesis and progression, and may become a new adjunct marker in the diagnosis and prognosis in cholangiocarcinoma
TMPRSS4 (show TMPRSS4 Proteins) is upregulated by silencing of TFPI-2 through aberrant DNA methylation (show HELLS Proteins) and contributes to oncogenesis in non-small cell lung cancer.
TFPI-2 is a down-regulated tumor suppressor gene in oral squamous cell carcinoma, probably involving epigenetic silencing mechanisms. The loss of TFPI-2 expression is a key event for oral tumorigenesis, especially in the process of tumor metastasis.
regulation of tissue factor pathway inhibitor-2 (TFPI-2) expression by lysine-specific demethylase 1 and 2
TFPI-2 in platelets from normal or pregnant subjects and in plasma from pregnant women binds FV/Va and regulates intrinsic coagulation and fibrinolysis
TFPI-2 downregulation can contribute to tumor invasion of hepatocellular carcinoma cells through alteration in the expression of metastasis-related genes.
A novel mouse model is presented and can be used to investigate the role of TFPI-2 in the process of atherosclerosis.
Over-expression of TFPI-2 promotes atherosclerotic plaque stability, which may be related to inhibition of matrix metalloproteinases.
Bovine TFPI2 was compared to mouse TFPI2.
human and murine TFPI-2 have different functions in liver regulation during inflammation in the two species
Our data suggest that TFPI-2 may be an important regulator of aberrant angiogenesis associated with tumor growth/metastasis, cardiovascular diseases, chronic inflammation, or diabetes.
Deficiency for the histone methyltransferase EHMT2 (show EHMT2 Proteins) or for the Polycomb group protein EED (show EED Proteins), leads to biallelic expression of Tfpi2 in the extra-embryonic lineages, whereas the other genes in the cluster maintain correct imprinting.
Dynamic changes of Tfpi2 associated with Il-1beta (show IL1B Proteins) and Tnf-alpha (show TNF Proteins) in the development of acute lung injury are reported.
Bovine TFPI2 was cloned and its expression and characterization determined.
This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.
tissue factor pathway inhibitor 2
, tissue factor pathway inhibitor-2
, Tissue factor pathway inhibitor 2
, placental protein 5
, retinal pigment epithelium cell factor 1