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Tissue Factor Pathway Inhibitor 2 Proteins (TFPI2)

TFPI2 encodes a member of the Kunitz-type serine proteinase inhibitor family. Additionally we are shipping TFPI2 Antibodies (110) and TFPI2 Kits (37) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TFPI2 7980 P48307
TFPI2 21789 O35536
TFPI2 286926  
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Top TFPI2 Proteins at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_HEK-293 Cells Human His tag 50 μg Log in to see 2 to 3 Days
$341.00
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_HEK-293 Human His tag 10 μg Log in to see 2 to 3 Days
$262.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_HEK-293 Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$206.55
Details
HOST_Nicotiana benthamiana Human His tag Panel A show SDS-PAGE 15 % Coomassie Blue of AGV 212 trypsin inhibitor purified by Gel filtration. Lane 1: Precision Plus Protein Standards cat 161-0363 BIORAD, lane 2: AGV 212 1mg/mL. Panel B show lane 1: Kaleidoscope Prestained Standards cat 161-0324 BIORAD, lane 2: the same samples analyzed by Western Blot with specific antiserum. All bands observed shown the same peptide mass finger printing pattern, corresponding to AGV212. Post-translational modifications do exist among the different bands nevertheless they do not alter their activity The activity of the inhibitor is expressed as the amount of trypsin inhibited per milligram of inhibitor. The ability to prevent the hydrolysis of benzoyl-L-arginine ethyl ester hydrochloride by trypsin is measured by spectrophotometer. One mg protein will inhibit 1-1.5 mg trypsin with activity of approximately 10, 000 BAEE units per mg protein. 1 mg Log in to see 6 to 7 Days
$346.50
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$792.00
Details

TFPI2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , ,
,
Mouse (Murine) ,
,
Rat (Rattus)

Top referenced TFPI2 Proteins

  1. Human TFPI2 Protein expressed in HEK-293 - ABIN2666517 : Lwaleed, Bass: Tissue factor pathway inhibitor: structure, biology and involvement in disease. in The Journal of pathology 2006 (PubMed)
    Show all 8 references for ABIN2666517

  2. Human TFPI2 Protein expressed in Human Cells - ABIN2003028 : Miyagi, Koshikawa, Yasumitsu, Miyagi, Hirahara, Aoki, Misugi, Umeda, Miyazaki: cDNA cloning and mRNA expression of a serine proteinase inhibitor secreted by cancer cells: identification as placental protein 5 and tissue factor pathway inhibitor-2. in Journal of biochemistry 1995 (PubMed)

  3. Human TFPI2 Protein expressed in HEK-293 Cells - ABIN2181806 : Rao, Liu, Peavey, Woodley: Novel extracellular matrix-associated serine proteinase inhibitors from human skin fibroblasts. in Archives of biochemistry and biophysics 1995 (PubMed)

More Proteins for Tissue Factor Pathway Inhibitor 2 (TFPI2) Interaction Partners

Zebrafish Tissue Factor Pathway Inhibitor 2 (TFPI2) interaction partners

Human Tissue Factor Pathway Inhibitor 2 (TFPI2) interaction partners

  1. Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 (show PRSS3 Proteins) accumulated tissue factor pathway inhibitor-2 (TFPI-2) in the matrix.

  2. Hypermethylation of TFPI2 promoter is increased in inflamed colon tissue.

  3. DNA methylation of TFPI2 may play an important role in the carcinogenesis of cervical cancer and that the differential methylation of TFPI2 may at least partially explain the disparity in cervical cancer incidence between Uygur and Han women.

  4. our findings suggested that the differential expression of MMP-2 (show MMP2 Proteins) and TFPI-2 have a negative correlation in pancreatic carcinoma

  5. Our finding suggests that the decreased expression of TFPI-2 may play an important role in the carcinogenesis and progression, and may become a new adjunct marker in the diagnosis and prognosis in cholangiocarcinoma

  6. TMPRSS4 (show TMPRSS4 Proteins) is upregulated by silencing of TFPI-2 through aberrant DNA methylation (show HELLS Proteins) and contributes to oncogenesis in non-small cell lung cancer.

  7. TFPI-2 is a down-regulated tumor suppressor gene in oral squamous cell carcinoma, probably involving epigenetic silencing mechanisms. The loss of TFPI-2 expression is a key event for oral tumorigenesis, especially in the process of tumor metastasis.

  8. regulation of tissue factor pathway inhibitor-2 (TFPI-2) expression by lysine-specific demethylase 1 and 2

  9. TFPI-2 in platelets from normal or pregnant subjects and in plasma from pregnant women binds FV/Va and regulates intrinsic coagulation and fibrinolysis

  10. TFPI-2 downregulation can contribute to tumor invasion of hepatocellular carcinoma cells through alteration in the expression of metastasis-related genes.

Mouse (Murine) Tissue Factor Pathway Inhibitor 2 (TFPI2) interaction partners

  1. A novel mouse model is presented and can be used to investigate the role of TFPI-2 in the process of atherosclerosis.

  2. Over-expression of TFPI-2 promotes atherosclerotic plaque stability, which may be related to inhibition of matrix metalloproteinases.

  3. Bovine TFPI2 was compared to mouse TFPI2.

  4. human and murine TFPI-2 have different functions in liver regulation during inflammation in the two species

  5. Our data suggest that TFPI-2 may be an important regulator of aberrant angiogenesis associated with tumor growth/metastasis, cardiovascular diseases, chronic inflammation, or diabetes.

  6. Deficiency for the histone methyltransferase EHMT2 (show EHMT2 Proteins) or for the Polycomb group protein EED (show EED Proteins), leads to biallelic expression of Tfpi2 in the extra-embryonic lineages, whereas the other genes in the cluster maintain correct imprinting.

  7. Dynamic changes of Tfpi2 associated with Il-1beta (show IL1B Proteins) and Tnf-alpha (show TNF Proteins) in the development of acute lung injury are reported.

Cow (Bovine) Tissue Factor Pathway Inhibitor 2 (TFPI2) interaction partners

  1. Bovine TFPI2 was cloned and its expression and characterization determined.

TFPI2 Protein Profile

Protein Summary

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with TFPI2

  • tissue factor pathway inhibitor 2 (tfpi2)
  • tissue factor pathway inhibitor 2 (TFPI2)
  • tissue factor pathway inhibitor 2 (LOC100218198)
  • Tissue factor pathway inhibitor 2 (tfpi2)
  • papilin-like (LOC100718882)
  • tissue factor pathway inhibitor 2 (Tfpi2)
  • tissue factor pathway inhibitor 2-like (LOC100520144)
  • AV000670 protein
  • MGC68843 protein
  • MGC108301 protein
  • PP5 protein
  • PP5/TFPI-2 protein
  • REF1 protein
  • si:ch211-262k23.2 protein
  • TFPI-2 protein
  • tfpi2 protein

Protein level used designations for TFPI2

tissue factor pathway inhibitor 2 , tissue factor pathway inhibitor-2 , Tissue factor pathway inhibitor 2 , placental protein 5 , retinal pigment epithelium cell factor 1 , TFPI-2

GENE ID SPECIES
379525 Xenopus laevis
463540 Pan troglodytes
548483 Xenopus (Silurana) tropicalis
560339 Danio rerio
700850 Macaca mulatta
100218198 Taeniopygia guttata
100305210 Oncorhynchus mykiss
100718882 Cavia porcellus
7980 Homo sapiens
21789 Mus musculus
286926 Rattus norvegicus
360007 Bos taurus
475230 Canis lupus familiaris
420561 Gallus gallus
101113838 Ovis aries
100520144 Sus scrofa
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