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Tumor Necrosis Factor Receptor Superfamily, Member 13B Proteins (TNFRSF13B)

The protein encoded by TNFRSF13B is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. Additionally we are shipping TNFRSF13B Antibodies (153) and TNFRSF13B Kits (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFRSF13B 23495 O14836
TNFRSF13B 57916 Q9ET35
Rat TNFRSF13B TNFRSF13B 691719  
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Top TNFRSF13B Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Human Fc Tag   50 μg Log in to see 5 to 8 Days
$336.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Mouse Fc Tag   10 μg Log in to see 10 to 12 Days
$135.88
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$882.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 7 to 9 Days
$328.21
Details

TNFRSF13B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) , ,
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Top referenced TNFRSF13B Proteins

  1. Mouse (Murine) TNFRSF13B Protein expressed in Escherichia coli (E. coli) - ABIN2667577 : He, Santamaria, Xu, Cols, Chen, Puga, Shan, Xiong, Bussel, Chiu, Puel, Reichenbach, Marodi, Döffinger, Vasconcelos, Issekutz, Krause, Davies, Li, Grimbacher, Plebani, Meffre, Picard et al.: The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. ... in Nature immunology 2010 (PubMed)
    Show all 6 references for ABIN2667577

  2. Human TNFRSF13B Protein expressed in Human Cells - ABIN2004906 : Wu, Bressette, Carrell, Kaufman, Feng, Taylor, Gan, Cho, Garcia, Gollatz, Dimke, LaFleur, Migone, Nardelli, Wei, Ruben, Ullrich, Olsen, Kanakaraj, Moore, Baker: Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS. in The Journal of biological chemistry 2000 (PubMed)
    Show all 4 references for ABIN2004906

  3. Human TNFRSF13B Protein expressed in Escherichia coli (E. coli) - ABIN1098781 : von Bülow, Bram: NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 2 references for ABIN1098781

  4. Human TNFRSF13B Protein expressed in Human - ABIN1344232 : Huard, Tran, Benkhoucha, Manzin-Lorenzi, Santiago-Raber: Selective APRIL blockade delays systemic lupus erythematosus in mouse. in PLoS ONE 2012 (PubMed)

More Proteins for Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) interaction partners

  1. SNPs rs9514828 (BAFF (show TNFSF13B Proteins)), rs3803800 (APRIL) and rs4985726 (TACI) may be associated with the risk of development of B-cell chronic lymphocytic leukemia in a Polish population.

  2. serum levels not associated with disease activity in MPO (show MPO Proteins)-ANCA-associated renal vasculitis

  3. In this review, we aim at giving an insight into the genetics underlying the CVID and particularly at outlining the role of TACI and its relative contribution to the development of CVID-like phenotypes in human.

  4. TNFRSF13B hemizygosity does not recapitulate autoimmune features of common variable immune deficiency -associated C104R and A181E TNFRSF13B mutations, which likely encode dominant negative products, but instead reveals selective TACI haploinsufficiency at later stages of B-cell development.

  5. Common variable immune d (show TNFSF13B Proteins)eficiency patients with heterozygous mutations in TACI alleles increase susceptibility to autoimmune diseases.

  6. The study demonstrated that there is a remarkable interindividual variability of TACI expression in chronic lymphocytic leukemia, although the majority of patients display low to undetectable TACI.

  7. Variants of TNFRSF13B were associated with common variable immunodeficiency.

  8. only Transmembrane Activator and CAML Interactor (TACI) correlates with the MMC's capability to ligate BAFF (show TNFSF13B Proteins). Additionally, the level of expression of TACI correlates with the level of the MMC's BM dependency

  9. Data show significant differences in expression of tumour necrosis factor (show TNF Proteins) family (BAFF (show TNFSF13B Proteins)) receptors BAFF-R (show TNFRSF13C Proteins), BCMA (show TNFRSF17 Proteins) and TACI in patients with and without anti-Jo-1 or anti-Ro52 (show TRIM21 Proteins)/anti-Ro60 (show TROVE2 Proteins) autoantibodies.

  10. Although the transcriptional controls for alternative splicing of TACI isoforms remain unknown, differential signals via isoforms may control plasma-cell generation.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) interaction partners

  1. splenic B cells from TACI-deficient (TACI- / -) mice were unable to secrete IL-10 (show IL10 Proteins) following TLR stimulation, and TACI- / - mice had undetectable basal serum concentrations of IL-10 (show IL10 Proteins).

  2. Data show that production of autoantibodies in B cell-activating factor (show TNFSF13B Proteins) of the TNF (show TNF Proteins) family (BAFF (show TNFSF13B Proteins)) is dependent on tumor necrosis factor (show TNF Proteins) receptor superfamily, member 13b protein (TACI) expression by B cells.

  3. Taci (-/-) mice and BAFF (show TNFSF13B Proteins) transgenic mice both develop signs of human Systemic Lupus Erythematosus.

  4. Elimination of B lymphocyte stimulator (show TNFSF13B Proteins) receptor 3 (BR-3) and TACI inhibits the development of SLE in NZM mice.

  5. TACI deficiency has a role in alternatively activated macrophage phenotype and susceptibility to Leishmania infection

  6. Heteromers consisting of one BAFF (show TNFSF13B Proteins) and two APRIL bind to receptor TACI, BCMA (show TNFRSF17 Proteins) but not to BAFFR (show TNFRSF13C Proteins).

  7. Mice lacking TACI are able to clear Citrobacter rodentium, a model pathogen for severe human enteritis, more rapidly than did wild type mice.

  8. reduced TACI expression is responsible for the unresponsiveness of XID (show BTK Proteins) mouse to TI-2 Ags (show GLA Proteins) and BCR (show BCR Proteins) activation controls TACI expression.

  9. Although we have found that TACI is dispensable for controlling B. hermsii infection, mice deficient in BAFFR or BAFF exhibit impairment in B. hermsii-specific IgM responses and clearance of bacteremia.

  10. Data indicate that APRIL expression accelerates the onset of TCL1 (show TCL1A Proteins)-driven leukemia formation mainly through TACI activation.

TNFRSF13B Protein Profile

Protein Summary

The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17.

Gene names and symbols associated with TNFRSF13B

  • tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B)
  • tumor necrosis factor receptor superfamily, member 13b (Tnfrsf13b)
  • tumor necrosis factor receptor superfamily, member 13B (Tnfrsf13b)
  • 1200009E08Rik protein
  • CD267 protein
  • CVID protein
  • CVID2 protein
  • RYZN protein
  • Taci protein
  • TNFRSF13B protein
  • TNFRSF14B protein

Protein level used designations for TNFRSF13B

tumor necrosis factor receptor superfamily, member 13B , tumor necrosis factor receptor superfamily member 13B , transmembrane activator and CAML interactor , tumor necrosis factor receptor 13B , transmembrane activator and calcium-modulating and cyclophilin ligand interactor

GENE ID SPECIES
609580 Canis lupus familiaris
617948 Bos taurus
744388 Pan troglodytes
770275 Gallus gallus
23495 Homo sapiens
57916 Mus musculus
691719 Rattus norvegicus
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