TACI Protein (AA 1-166) (His tag)

Catalog No. ABIN1880646

Product Details

Target: TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))

Protein Type: Recombinant

Protein Characteristics: AA 1-166

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This TACI protein is labelled with His tag.

Purpose: Recombinant Human T-lymphocyte Surface Antigen Ly-9/SLAMF3/CD229 (C-6His)

Sequence: KDSAPTVVSG ILGGSVTLPL NISVDTEIEN VIWIGPKNAL AFARPKENVT IMVKSYLGRL DITKWSYSLC ISNLTLNDAG SYKAQINQRN FEVTTEEEFT LFVYEQLQEP QVTMKSVKVS ENFSCNITLM CSVKGAEKSV LYSWTPREPH ASESNGGSIL TVSRTPCDPD LPYICTAQNP VSQRSSLPVH VGQFCTDPGA SRGGTTGETV VGVLGEPVTL PLALPACRDT EKVVWLFNTS IISKEREEAA TADPLIKSRD PYKNRVWVSS QDCSLKISQL KIEDAGPYHA YVCSEASSVT SMTHVTLLIY RRLRKPKITW SLRHSEDGIC RISLTCSVED GGNTVMYTWT PLQKEAVVSQ GESHLNVSWR SSENHPNLTC TASNPVSRSS HQFLSENICS GPERNTKHHH HHH

Characteristics: Recombinant Human Tumor necrosis factor receptor superfamily member 13B/TNFRSF13B is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-His166) of Human TNFRSF13B fused with a polyhistidine tag and FC tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))

Alternative Name: TNFRSF13B (TNFRSF13B Products)

Synonyms: CD267 Protein, CVID Protein, CVID2 Protein, RYZN Protein, TACI Protein, TNFRSF14B Protein, TNFRSF13B Protein, 1200009E08Rik Protein, Taci Protein, TNF receptor superfamily member 13B Protein, tumor necrosis factor receptor superfamily, member 13b Protein, TNFRSF13B Protein, Tnfrsf13b Protein

Sub Type: Fusionprotein

Background: Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), is also known as Transmembrane activator and CAML interactorand, CD267 and TACI. TNFRSF13B is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system. TNFRSF13B is highly expressed in spleen, small intestine, thymus and peripheral blood leukocytes. TNFRSF13B mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. TNFRSF13B is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. Defects in TNFRSF13B are the cause of immunodeficiency common variable type 2 (CVID2) and cause of immunoglobulin A deficiency 2 (IGAD2).
Alternative Names: Tumor necrosis factor receptor superfamily member 13B, TNFRSF13B, Transmembrane activator, CAML interactorand, CD267,TACI.

Molecular Weight: 45.6 kDa

UniProt: Q9HBG7