TACI Protein (AA 2-166) (Fc Tag)
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- Target See all TACI (TNFRSF13B) Proteins
- TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-166
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TACI protein is labelled with Fc Tag.
- Purpose
- Human TACI/TNFRSF13B Protein
- Sequence
- Ser2-Thr166
- Characteristics
- Recombinant Human TACI/TNFRSF13B Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser2-Thr166.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human BAFF Trimer, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA. See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
- Alternative Name
- TACI (TNFRSF13B Products)
- Synonyms
- CD267 Protein, CVID Protein, CVID2 Protein, RYZN Protein, TACI Protein, TNFRSF14B Protein, TNFRSF13B Protein, 1200009E08Rik Protein, Taci Protein, TNF receptor superfamily member 13B Protein, tumor necrosis factor receptor superfamily, member 13b Protein, TNFRSF13B Protein, Tnfrsf13b Protein
- Background
- Transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) is one of the receptors of B cell activating factor of the tumor necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL). TACI is a regulator in the immune responses. TACI inhibits B cell expansion and promotes the differentiation and survival of plasma cells.
- Molecular Weight
- 45.3 kDa. Due to glycosylation, the protein migrates to 38-40 kDa and 50-55 kDa based on Tris-Bis PAGE result.
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