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The protein encoded by TNFRSF4 is a member of the TNF-receptor superfamily. Additionally we are shipping Tumor Necrosis Factor Receptor Superfamily, Member 4 Proteins (34) and Tumor Necrosis Factor Receptor Superfamily, Member 4 Kits (22) and many more products for this protein.
Showing 10 out of 210 products:
Cat (Feline) Monoclonal TNFRSF4 Primary Antibody for FACS, WB - ABIN180755
Arch, Thompson: 4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB. in Molecular and cellular biology 1998
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Rat (Rattus) Monoclonal TNFRSF4 Primary Antibody for FACS, IHC (fro) - ABIN120515
Mallett, Fossum, Barclay: Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor. in The EMBO journal 1990
Show all 3 references for ABIN120515
Rat (Rattus) Monoclonal TNFRSF4 Primary Antibody for FACS, IHC (fro) - ABIN120516
Paterson, Jefferies, Green, Brandon, Corthesy, Puklavec, Williams: Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. in Molecular immunology 1988
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Mouse (Murine) Monoclonal TNFRSF4 Primary Antibody for FACS - ABIN118276
Takeda, Oshima, Hayakawa, Akiba, Atsuta, Kobata, Kobayashi, Ito, Yagita, Okumura: CD27-mediated activation of murine NK cells. in Journal of immunology (Baltimore, Md. : 1950) 2000
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Human Monoclonal TNFRSF4 Primary Antibody for FACS, ELISA - ABIN610385
Eskelinen, Illert, Tanaka, Schwarzmann, Blanz, Von Figura, Saftig: Role of LAMP-2 in lysosome biogenesis and autophagy. in Molecular biology of the cell 2002
Mouse (Murine) Monoclonal TNFRSF4 Primary Antibody for FACS, IHC (fro) - ABIN118274
Higgins, McDonald, Whittle, Crockett, Shields, MacDonald et al.: Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an ... in Journal of immunology (Baltimore, Md. : 1950) 1999
Crystal structures and NMR data show that the Roquin (show RC3H1 Antibodies)-1 ROQ domain recognizes hexaloops in the SELEX-derived alternative decay element (ADE) and in an ADE-like variant present in the Ox40 3'-UTR (show UTS2R Antibodies) with identical binding modes.
The OX40-OX40 ligand (show TNFSF4 Antibodies) interaction up-regulates intracellular levels of reactive oxygen species in atherogenesis.
OX40 was highly expressed by intratumoral T cells, particularly those of the FoxP3 (show FOXP3 Antibodies)(+) regulatory T-cell (Treg) lineage.
OX40 and IL-7 (show IL7 Antibodies) play synergistic, but distinct roles in the homeostatic proliferation of CD4 (show CD4 Antibodies)(+) effector memory T cells
OX40-OX40L (show TNFSF4 Antibodies) interaction regulates the expression of NFATc1 (show NFATC1 Antibodies), which may play a critical role in atherosclerotic plaque formation, and may therefore have implications with pathophysiology of atherosclerosis.
During CD134 plus CD137 (show TNFRSF9 Antibodies) dual costimulation, IFN-gamma (show IFNG Antibodies) interacts with IL-2 (show IL2 Antibodies) through distinct mechanisms to program maximal expression of effector molecules in antigen-responding T-cells.
OX40 stimulation of virus-specific CD4 (show CD4 Antibodies) T cells promoted expression of the transcriptional repressor Blimp-1 (show PRDM1 Antibodies) and diverted the majority of cells away from follicular Th cell differentiation.
interruption of the OX40-OX40L signaling pathway, with decreases in dietary cholesterol, induces regression of atherosclerosis by induction of IL-5-producing T cells and oxidized low-density lipoprotein-specific IgM and reductions in Th2 and mast cells.
OX40-OX40L (show TNFSF4 Antibodies) interaction promotes proliferation and activation of lymphocytes via NFATc1 (show NFATC1 Antibodies) in ApoE (show APOE Antibodies)-deficient mice.
These data show that OX40-OX40L (show TNFSF4 Antibodies) signaling contributes to the evolution of the adaptive immune response to an allograft via the differential control of alloreactive effector and regulatory T cell survival.
Low OX40 expression is associated with colorectal cancer.
OX40 and its ligand are co stimulators for T lymphocytes.
These studies provide the first direct evidence that ligation of tumour necrosis factor (show TNF Antibodies) superfamily members and their cognate receptors is important for the control of viral lytic replication.
Malaria patients and Plasmodium-infected rodents exhibit enhanced expression of the co-stimulatory receptor OX40 on CD4 (show CD4 Antibodies) T cells, which is abrogated following coordinate PD-1 (show PDCD1 Antibodies) co-inhibitory pathways, which are also upregulated during malaria.
Identified two key amino acid residues within CD134 that are required for its interaction with herpesvirus 6B (HHV-6B) and for HHV-6B entry into cells. One of the residues (K79) allows access of the HHV-6B ligand to CD134.
TL1A (show TNFSF15 Antibodies) increases expression of CD25 (show IL2RA Antibodies), LFA-1 (show ITGAL Antibodies), CD134 and CD154 (show CD40LG Antibodies), and induces IL-22 (show IL22 Antibodies) and GM-CSF (show CSF2 Antibodies) production from effector CD4 (show CD4 Antibodies) T-cells
Data indicate that soluble OX40 and sOX40L plasma levels are increased in early rheumatoid arthritis patients.
High expression of OX40 is associated with type 1 diabetes.
A cysteine-rich domain of CD134 that is critical for binding to the HHV-6B glycoprotein gH/gL/gQ1/gQ2 complex and HHV-6B infection.
cirrhotic and hepatocellular carcinoma fragments moderately and highly infiltrated by Tregs, respectively, expressing OX40
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
tumor necrosis factor receptor superfamily, member 4
, tumor necrosis factor receptor superfamily member 4
, OX40 antigen
, OX40L receptor
, tax-transcriptionally activated glycoprotein 1
, ACT35 antigen
, ATC35 antigen
, CD134 antigen
, OX40 cell surface antigen
, OX40 homologue
, TAX transcriptionally-activated glycoprotein 1 receptor
, lymphoid activation antigene ACT35
, tax-transcriptionally activated glycoprotein 1 receptor
, MRC OX40
, Tax-transcriptionally activated glycoprotein 1
, tumor necrosis factor (ligand) superfamily member 4
, tumor necrosis factor superfamily, member 4