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anti-UACA (UACA) Antibodies

Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Additionally we are shipping UACA Kits (10) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UACA 55075 Q9BZF9
UACA 72565 Q8CGB3
UACA 315732  
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Top anti-UACA Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IF (cc), IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Cow Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Cow Rabbit FITC IF (cc), IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Cow Rabbit Alexa Fluor 350 IF (cc), IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Cow Rabbit Alexa Fluor 488 IF (cc), IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Cow Rabbit Alexa Fluor 555 IF (cc), IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Cow Rabbit Alexa Fluor 647 IF (cc), IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Cow Rabbit Alexa Fluor 594 IF (cc), IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

UACA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Rat (Rattus) ,


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Top referenced anti-UACA Antibodies

  1. Cow (Bovine) Polyclonal UACA Primary Antibody for IF (cc), IF (p) - ABIN717191 : Akiyama: Identification of UACA, EXOSC9, and ??X2 in bovine periosteal cells by mass spectrometry and immunohistochemistry. in Analytical and bioanalytical chemistry 2014 (PubMed)

More Antibodies against UACA Interaction Partners

Human UACA interaction partners

  1. The down-regulation of APIP (show APIP Antibodies) and UACA expression suggests that the threshold to activate the apoptosome apparatus may be decreased in non-small cell lung cancer cells.

  2. UACA is a novel candidate for eye muscle autoantigens in thyroid-associated ophthalmopathy

Mouse (Murine) UACA interaction partners

  1. Nucling plays an important role in mammary gland involution by regulating NF-kappaB (show NFKB1 Antibodies) and STAT3 (show STAT3 Antibodies) signaling pathways

  2. Findings indicate that UACA functions as a Rab39A effector in the retinoic acid-induced differentiation of Neuro2A cells.

  3. Data from knockout mice suggest that nucling plays important role in induction of apoptosis in liver/hepatocytes damaged by cytotoxic stressors; nucling acts through modulation of NFkappaB signaling.

  4. Nucling expression is induced by canonical NF-kappaB (show NFKB1 Antibodies) signalling pathway, whereas Nucling is undergoing proteasome degradation, as well as being cleaved by caspase (show CASP3 Antibodies) system under stress conditions

  5. Nucling deficiency could be a powerful tool to reveal the NF-kappaB (show NFKB1 Antibodies)-related molecular networks leading to hepatitis and hepatocellular carcinoma development.

  6. Nucling was shown to interfere with NF-kappaB (show NFKB1 Antibodies) activation via the nuclear translocation process of NF-kappaB (show NFKB1 Antibodies)/p65 (show NFkBP65 Antibodies), thus inhibiting the expression of galectin-3 (show LGALS3 Antibodies).

  7. Nucling recruits and transports the apoptosome complex during stress-induced apoptosis

  8. These results indicate an important role for Nucling in MPTP (show PTPN2 Antibodies)-induced neuronal degeneration and suggest that the suppression of Nucling would be of therapeutic benefit for the treatment of neurodegeneration in PD.

  9. a novel function of Nucling as a suppressor of nuclear factor-kappaB, mediated by its cytoplasmic retention through physical interaction

UACA Antigen Profile

Protein Summary

Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1. Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury (By similarity).

Gene names and symbols associated with anti-UACA (UACA) Antibodies

  • uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) antibody
  • uveal autoantigen with coiled-coil domains and ankyrin repeats (Uaca) antibody
  • 2700059D02Rik antibody
  • nucling antibody
  • RGD1560011 antibody

Protein level used designations for anti-UACA (UACA) Antibodies

nuclear membrane binding protein , uveal autoantigen with coiled coil domains and ankyrin repeats , nuclear membrane binding protein NUCLING , nuclear membrane-binding protein , beta-actin-binding protein , betaCAP73 , uveal autoantigen with coiled-coil domains and ankyrin repeats protein

GENE ID SPECIES
55075 Homo sapiens
72565 Mus musculus
281559 Bos taurus
315732 Rattus norvegicus
403704 Canis lupus familiaris
Selected quality suppliers for anti-UACA (UACA) Antibodies
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