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WAP Four-Disulfide Core Domain 1 Proteins (WFDC1)

WFDC1 encodes a member of the WAP-type four disulfide core domain family. Additionally we are shipping WFDC1 Antibodies (65) and WFDC1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
WFDC1 58189 Q9HC57
WFDC1 67866 Q9ESH5
WFDC1 171112 O70280
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Top WFDC1 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,442.00
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,454.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   500 μg Log in to see 3 to 4 Days
$437.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
HOST_Human Mouse Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

WFDC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)
Rat (Rattus)

More Proteins for WAP Four-Disulfide Core Domain 1 (WFDC1) Interaction Partners

Cow (Bovine) WAP Four-Disulfide Core Domain 1 (WFDC1) interaction partners

  1. refined the localization of the MOD locus to a 1.0-Mb interval by haplotype analysis, and found a one-nucleotide insertion in the WFDC1 gene, which resulted in a frame shift mutation and premature termination codon, causing Multiple ocular defects

Human WAP Four-Disulfide Core Domain 1 (WFDC1) interaction partners

  1. HIV-1 virus transfer among primary CD4 (show CD4 Proteins)+ T-lymphocytes was promoted by ectopic ps20 expression or by exogenous addition of recombinant ps20.

  2. results suggest a minor role, if any, of WFDC1 in hepatocarcinogenesis

  3. WFDC1/ps20 is down regulated but not frequently mutated in prostate cancer. It is expressed predominantly in the normal prostatic stroma. It might play a role in the maintenance of the normal extra cellular matrix milieu in the prostate.

  4. ps20 promoted HIV entry via fusion and augmented CD54 (show ICAM1 Proteins) integrin expression

  5. our data suggest an important role for WFDC1 in inhibiting proliferation of both tumors and senescent cells

  6. suggests that the tumor suppressive function of WFDC1 may be partially a result of up-regulated Dkk1 (show DKK1 Proteins) gene expression, which is known to be a potent inhibitor of the Wnt (show WNT2 Proteins) signaling pathway

Mouse (Murine) WAP Four-Disulfide Core Domain 1 (WFDC1) interaction partners

  1. WFDC1/ps20 modulates core host response mechanisms, in part, via regulation of osteopontin (show SPP1 Proteins) and MMP-9 (show MMP9 Proteins) activity. Release from WFDC1 regulation is likely a key component of inflammatory and repair response mechanisms.

  2. These data suggest roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to murine hepatitis virus -1 infection.

  3. ps20 may be a TGF-beta1 (show TGFB1 Proteins)-induced regulator of angiogenesis that functions by either promoting endothelial cell migration or by contributing to pericyte stabilization of newly formed vascular structures.

WFDC1 Protein Profile

Protein Summary

This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.

Gene names and symbols associated with WFDC1

  • WAP four-disulfide core domain 1 (WFDC1)
  • WAP four-disulfide core domain 1 (wfdc1)
  • WAP four-disulfide core domain 1 (Wfdc1)
  • 2310058A03Rik protein
  • ps20 protein
  • WFDC1 protein
  • zgc:158671 protein

Protein level used designations for WFDC1

WAP four-disulfide core domain 1 , WAP four-disulfide core domain protein 1 , WAP four-disulfide core domain 1 homolog , prostate stromal protein ps20 , ps20 growth inhibitor , 20-kDa prostate stromal protein , protein ps20

GENE ID SPECIES
454281 Pan troglodytes
489682 Canis lupus familiaris
505366 Bos taurus
560860 Danio rerio
58189 Homo sapiens
67866 Mus musculus
171112 Rattus norvegicus
395238 Gallus gallus
Selected quality suppliers for WFDC1 Proteins (WFDC1)
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