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WAP Four-Disulfide Core Domain 2 Proteins (WFDC2)

WFDC2 encodes a protein that is a member of the WFDC domain family. Additionally we are shipping WFDC2 Antibodies (140) and WFDC2 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
WFDC2 10406 Q14508
WFDC2 67701 Q9DAU7
Rat WFDC2 WFDC2 286888 Q8CHN3
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Top WFDC2 Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag WAP Four-Disulfide Core Domain 2 (WFDC2) (AA 31-124), (full length) protein (GST tag) 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$286.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Mammalian Cells Human His tag 50 μg Log in to see 13 to 16 Days
$1,083.50
Details
HOST_Human Cells Mouse His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Cells Dog Fc Tag 100 μg Log in to see 16 Days
$437.80
Details

WFDC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , , ,
, ,
Mouse (Murine)

Top referenced WFDC2 Proteins

  1. Human WFDC2 Protein expressed in Escherichia coli (E. coli) - ABIN1047932 : Kirchhoff, Habben, Ivell, Krull: A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors. in Biology of reproduction 1992 (PubMed)
    Show all 2 references for ABIN1047932

  2. Human WFDC2 Protein expressed in Wheat germ - ABIN1325310 : Eaton, Shallcross, Mael, Mears, Minkoff, Scoville, Whelan: Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing. in Analytical and bioanalytical chemistry 2015 (PubMed)

  3. Human WFDC2 Protein expressed in Human Cells - ABIN2005283 : LeBleu, Teng, OConnell, Charytan, Müller, Müller, Sugimoto, Kalluri: Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis. in Nature medicine 2013 (PubMed)

  4. Human WFDC2 Protein expressed in HEK-293 Cells - ABIN2181198 : Hellström, Raycraft, Hayden-Ledbetter, Ledbetter, Schummer, McIntosh, Drescher, Urban, Hellström: The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma. in Cancer research 2003 (PubMed)

More Proteins for WAP Four-Disulfide Core Domain 2 (WFDC2) Interaction Partners

Human WAP Four-Disulfide Core Domain 2 (WFDC2) interaction partners

  1. optimal cut-off values (HE4: 70pmol/l for all; CA125 (show MUC16 Proteins): 60U/ml for pre- and 35U/ml for postmenopausal women) could notably improve diagnostic performance in EOC detection in patients in southern China

  2. Results show that recombinant HE4 proteins are able to promote the proliferation of pancreatic and endometrial cancer cells suggesting that HE4 secreted from cancer cells may carry out paracrine and endocrine functions in cancer patients.

  3. Increased WFDC2 expression plays an important role in altering the estrogen pathway in ovarian cancer.

  4. Endometrial cancer patients with high HE4 expression have a poor prognosis.

  5. Data show that serum neuron-specific enolase (show ENO2 Proteins), cytokeratin 19 (show KRT19 Proteins) fragment 21-1, pro-gastrin-releasing peptide (show GRP Proteins), squamous cell carcinoma antigen, tissue inhibitor of metalloproteinase-1, and human epididymis protein 4 are not associated with brain metastases.

  6. In this report, we describe our use of capillary electrophoresis (CE) as the separation mechanism in the process of selecting DNA aptamers with affinity for the ovarian cancer biomarker HE4.

  7. Expression levels of ANXA2 (show ANXA2 Proteins) and HE4 were closely related to the malignant biological behavior of endometrial carcinoma

  8. High serum HE4 level at diagnosis is an independent determinant of poor prognosis in NSCLC.

  9. Authors examined the serum concentration of human epididymis protein (HE4) in patients with benign gynecological diseases complicated with chronic renal deficiency

  10. Body mass index does not influence HE4 levels in serum.

Mouse (Murine) WAP Four-Disulfide Core Domain 2 (WFDC2) interaction partners

  1. Causal testing implicates Wfdc2 and Hdac3 (show HDAC3 Proteins) as novel genes affecting high density lipoprotein levels

WFDC2 Protein Profile

Protein Summary

This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

Gene names and symbols associated with WFDC2

  • WAP four-disulfide core domain 2 (WFDC2)
  • WAP four-disulfide core domain 2 (wfdc2)
  • Epididymal secretory protein E4 (E4)
  • WAP four-disulfide core domain 2 (Wfdc2)
  • 1600023A02Rik protein
  • BE-20 protein
  • CE4 protein
  • dJ461P17.6 protein
  • EDDM4 protein
  • HE4 protein
  • re4 protein
  • si:ch211-153a8.3 protein
  • WAP5 protein
  • WFDC2 protein
  • WFDC3 protein

Protein level used designations for WFDC2

WAP four-disulfide core domain 2 , WAP four-disulfide core domain 3 , WAP four-disulfide core domain protein 2 , WAP domain containing protein HE4-V4 , epididymal protein 4 , epididymal secretory protein E4 , epididymis-specific, whey-acidic protein type, four-disulfide core , major epididymis-specific protein E4 , putative protease inhibitor WAP5 , WAP domain-containing protein HE4 , epididymal secretory protein 4 , epididymal protein BE-20

GENE ID SPECIES
419300 Gallus gallus
458283 Pan troglodytes
618044 Bos taurus
100074492 Ornithorhynchus anatinus
556600 Danio rerio
396987 Sus scrofa
10406 Homo sapiens
67701 Mus musculus
286888 Rattus norvegicus
403919 Canis lupus familiaris
100009206 Oryctolagus cuniculus
Selected quality suppliers for WFDC2 Proteins (WFDC2)
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