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WAP Four-Disulfide Core Domain 2 Proteins (WFDC2)

WFDC2 encodes a protein that is a member of the WFDC domain family. Additionally we are shipping WFDC2 Antibodies (148) and WFDC2 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
WFDC2 10406 Q14508
WFDC2 67701 Q9DAU7
Rat WFDC2 WFDC2 286888 Q8CHN3
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Top WFDC2 Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag WAP Four-Disulfide Core Domain 2 (WFDC2) (AA 31-124), (full length) protein (GST tag) 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$286.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Mammalian Cells Human His tag 50 μg Log in to see 13 to 16 Days
$1,083.50
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
$385.00
Details
HOST_Human Cells Mouse His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details

WFDC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, ,
Mouse (Murine)

Top referenced WFDC2 Proteins

  1. Human WFDC2 Protein expressed in Escherichia coli (E. coli) - ABIN1047932 : Kirchhoff, Habben, Ivell, Krull: A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors. in Biology of reproduction 1992 (PubMed)
    Show all 2 references for ABIN1047932

  2. Human WFDC2 Protein expressed in Wheat germ - ABIN1325310 : Eaton, Shallcross, Mael, Mears, Minkoff, Scoville, Whelan: Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing. in Analytical and bioanalytical chemistry 2015 (PubMed)

  3. Human WFDC2 Protein expressed in Human Cells - ABIN2005283 : LeBleu, Teng, OConnell, Charytan, Müller, Müller, Sugimoto, Kalluri: Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis. in Nature medicine 2013 (PubMed)

  4. Human WFDC2 Protein expressed in HEK-293 Cells - ABIN2181198 : Hellström, Raycraft, Hayden-Ledbetter, Ledbetter, Schummer, McIntosh, Drescher, Urban, Hellström: The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma. in Cancer research 2003 (PubMed)

More Proteins for WAP Four-Disulfide Core Domain 2 (WFDC2) Interaction Partners

Human WAP Four-Disulfide Core Domain 2 (WFDC2) interaction partners

  1. HE4 had more potential than CA125 (show MUC16 Proteins).

  2. High serum HE-4 levels were associated with Endometrial Cancer.

  3. High HE4 expression is associated with Ovarian Tumors.

  4. High correlation with MRI (show C7ORF49 Proteins) parameters related to neoangiogenesis may indicate signaling pathway of HE4.

  5. The aim of the study was to establish whether preoperative serum levels of HE4 and CA125 (show MUC16 Proteins) could be a good predictor for lymphadenectomy in the early stage of endometrioid adenocarcinoma of the uterus.

  6. Data suggest that the combination of epididymis protein 4 (HE4) and CA125 (show MUC16 Proteins) may be recommended as potential biomarkers in the preliminary differential diagnosis of between epithelial ovarian cancer (EOC) and peritoneal tuberculosis (PTB (show PTBP1 Proteins)).

  7. findings suggested that serum HE4 was a better biomarker in early lung cancer than other frequently-used biomarkers

  8. HE4 is a promising biomarker for the early diagnosis of epithelial ovarian cancer [review]

  9. HE4 alone and even more the combined analysis of CA125 (show MUC16 Proteins) and HE4 using risk of malignancy algorithm improve the diagnostic accuracy of adnexal masses, especially in early ovarian cancer.

  10. Data suggest that overexpressed human epididymis protein 4 (HE4) played an important role in ovarian cancer progression and metastasis and that HE4 has the potential to serve as therapeutic target for ovarian cancer.

Mouse (Murine) WAP Four-Disulfide Core Domain 2 (WFDC2) interaction partners

  1. Causal testing implicates Wfdc2 and Hdac3 (show HDAC3 Proteins) as novel genes affecting high density lipoprotein levels

WFDC2 Protein Profile

Protein Summary

This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

Gene names and symbols associated with WFDC2

  • WAP four-disulfide core domain 2 (WFDC2)
  • WAP four-disulfide core domain 2 (wfdc2)
  • Epididymal secretory protein E4 (E4)
  • WAP four-disulfide core domain 2 (Wfdc2)
  • 1600023A02Rik protein
  • BE-20 protein
  • CE4 protein
  • dJ461P17.6 protein
  • EDDM4 protein
  • HE4 protein
  • re4 protein
  • si:ch211-153a8.3 protein
  • WAP5 protein
  • WFDC2 protein
  • WFDC3 protein

Protein level used designations for WFDC2

WAP four-disulfide core domain 2 , WAP four-disulfide core domain 3 , WAP four-disulfide core domain protein 2 , WAP domain containing protein HE4-V4 , epididymal protein 4 , epididymal secretory protein E4 , epididymis-specific, whey-acidic protein type, four-disulfide core , major epididymis-specific protein E4 , putative protease inhibitor WAP5 , WAP domain-containing protein HE4 , epididymal secretory protein 4 , epididymal protein BE-20

GENE ID SPECIES
419300 Gallus gallus
458283 Pan troglodytes
618044 Bos taurus
100074492 Ornithorhynchus anatinus
556600 Danio rerio
396987 Sus scrofa
10406 Homo sapiens
67701 Mus musculus
286888 Rattus norvegicus
403919 Canis lupus familiaris
100009206 Oryctolagus cuniculus
Selected quality suppliers for WFDC2 Proteins (WFDC2)
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