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WFDC2 Protein (AA 28-124) (Fc Tag)

WFDC2 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274791
  • Target See all WFDC2 Proteins
    WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 28-124
    Origin
    • 11
    • 1
    • 1
    • 1
    Dog
    Source
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This WFDC2 protein is labelled with Fc Tag.
    Purpose
    Canine HE4 Protein
    Sequence
    Gly28-Phe124
    Characteristics
    Recombinant Canine HE4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly28-Phe124.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))
    Alternative Name
    HE4 (WFDC2 Products)
    Synonyms
    WFDC3 Protein, WFDC2 Protein, si:ch211-153a8.3 Protein, EDDM4 Protein, HE4 Protein, WAP5 Protein, dJ461P17.6 Protein, 1600023A02Rik Protein, re4 Protein, CE4 Protein, BE-20 Protein, WAP four-disulfide core domain 2 Protein, WFDC2 Protein, wfdc2 Protein, Wfdc2 Protein
    Background
    The ovarian cancer biomarker HE4 is known to promote proliferation, metastasis, chemoresistance, and suppression of cytotoxic lymphocytes. HE4 has the ability to affect signaling events and gene expression in multiple cell types of the tumor microenvironment, which could contribute to angiogenesis and altered immunogenic responses in ovarian cancer.
    Molecular Weight
    37.06 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
    UniProt
    Q28894
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