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Browse our COLEC12 Proteins (COLEC12)

Full name:
Collectin Sub-Family Member 12 Proteins (COLEC12)
On are 10 Collectin Sub-Family Member 12 (COLEC12) Proteins from 5 different suppliers available. Additionally we are shipping COLEC12 Antibodies (59) and COLEC12 Kits (4) and many more products for this protein. A total of 83 COLEC12 products are currently listed.
CL-P1, CLP1, COLEC12, hm:zeh0853, id:ibd2826, NSR2, sb:cb377, Scara4, si:ch211-212m21.5, SRCL
list all proteins Gene Name GeneID UniProt
COLEC12 81035 Q5KU26
COLEC12 140792 Q8K4Q8
COLEC12 361289 Q4V885

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COLEC12 Proteins (COLEC12) by Origin

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Top referenced COLEC12 Proteins

  1. Rat (Rattus) COLEC12 Protein expressed in Baculovirus infected Insect Cells - ABIN2009576 : Danielsen, Sylvestersen, Bekker-Jensen, Szklarczyk, Poulsen, Horn, Jensen, Mailand, Nielsen: Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. in Molecular & cellular proteomics : MCP 2011 (PubMed)

More Proteins for COLEC12 Interaction Partners

Human Collectin Sub-Family Member 12 (COLEC12) interaction partners

  1. rs17684886 (ZNRF1 (show ZNRF1 Proteins)) and rs599019 (COLEC12) are associated with diabetic retinopathy and rs6427247 (SCYL1BP1 (show GORAB Proteins)) and rs899036 (API5 (show API5 Proteins)) are associated with severe diabetic retinopathy in Chinese patients with type 2 diabetes

  2. The common presence of Lewis(x (show FUT4 Proteins)) groups in granule protein glycans can thus target granule proteins for clearance by SRCL.

  3. The Le(x) residues of both, CEACAM1 (show CEACAM1 Proteins) and CEA (show CEACAM5 Proteins), interact with the human Le(x)-binding glycan receptors DC-SIGN (show CD209 Proteins) and SRCL.

  4. haplotype structure of the CL-P1 gene obtained from six single-nucleotide polymorphisms that were genotyped with 108 alleles in Japanese subjects

  5. SRCL is expressed in some but not all nurse-like cells; its C-type lectin (show MBL2 Proteins) domain binds specifically to several carbohydrates including GalNAc, T and Tn antigen in a Ca2 (show CA2 Proteins)+-dependent manner.

  6. SRCL might be involved in selective clearance of specific desialylated glycoproteins from circulation and/or interaction of cells bearing Lewis(x (show FUT4 Proteins))-type structures with the vascular endothelium

  7. CL-P1 is not a common membrane protein on endothelial cells found in normal tissues under steady state conditions.

  8. CL-P1 predominantly mediated phagocytosis for fungi in vascular endothelia.

Mouse (Murine) Collectin Sub-Family Member 12 (COLEC12) interaction partners

  1. Structural analysis of carbohydrate-recognition domain of SRCL in complex with Lewis(x (show FUT4 Proteins)) and mutagenesis show the basis for this specificity, which is analogous to how selectins and DC-SIGN (show CD209 Proteins) bind to related fucosylated glycans [scavenger receptor C]

  2. CL-P1 predominantly mediated phagocytosis for fungi in vascular endothelia.

COLEC12 Protein Profile

Protein Summary

This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.

Alternative names and synonyms associated with COLEC12

  • collectin sub-family member 12 (COLEC12)
  • collectin sub-family member 12 (LOC100136716)
  • collectin sub-family member 12 (colec12)
  • collectin sub-family member 12 (LOC100342125)
  • collectin sub-family member 12 (Colec12)
  • CL-P1 protein
  • CLP1 protein
  • COLEC12 protein
  • hm:zeh0853 protein
  • id:ibd2826 protein
  • NSR2 protein
  • sb:cb377 protein
  • Scara4 protein
  • si:ch211-212m21.5 protein
  • SRCL protein

Protein level used designations for COLEC12

collectin sub-family member 12 , collectin-12-like , collectin placenta protein 1 , collectin-12 , hCL-P1 , nurse cell scavenger receptor 2 , scavenger receptor class A, member 4 , scavenger receptor with C-type lectin , CL-P1 , CL-3 , cCL-3 , collectin 1 precursor CL-3 , collectin-3 , cb377 , zCL-P1 , zeh0853

468616 Pan troglodytes
700031 Macaca mulatta
100136716 Oncorhynchus mykiss
100379961 Xenopus (Silurana) tropicalis
100392117 Callithrix jacchus
100342125 Oryctolagus cuniculus
100580368 Nomascus leucogenys
81035 Homo sapiens
140792 Mus musculus
361289 Rattus norvegicus
421061 Gallus gallus
504741 Bos taurus
607342 Canis lupus familiaris
558942 Danio rerio
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