LNPEP antibody (C-Term)
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- Target See all LNPEP Antibodies
- LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LNPEP antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Specificity
- At least three isoforms are known to exist, this antibody will detect all three isoforms. Despite its predicted molecular weight, LNPEP often migrates at 165kD in SDS-PAGE.
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- LNPEP antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human LNPEP.
- Isotype
- IgG
- Top Product
- Discover our top product LNPEP Primary Antibody
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- Application Notes
- LNPEP antibody can be used for detection of LNPEP by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
- Comment
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(CT) insulin-responsive aminopeptidase
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Storage
- 4 °C/-20 °C
- Storage Comment
- LNPEP antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Expiry Date
- 12 months
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- Target
- LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))
- Alternative Name
- LNPEP (LNPEP Products)
- Synonyms
- fb73h12 antibody, wu:fb73h12 antibody, zgc:66103 antibody, 2010309L07Rik antibody, 4732490P18Rik antibody, CAP antibody, IRAP antibody, PLAP antibody, gp160 antibody, vp165 antibody, P-LAP antibody, Vp165 antibody, LNPEP antibody, leucyl and cystinyl aminopeptidase antibody, leucyl/cystinyl aminopeptidase L homeolog antibody, leucyl/cystinyl aminopeptidase antibody, LNPEP antibody, lnpep.L antibody, lnpep antibody, Lnpep antibody
- Background
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LNPEP, also known as insulin-responsive aminopeptidase (IRAP), was initially identified as an abundant protein that is associated with specialized endosomes termed GLUT4 storage vesicles (GSVs) in adipocytes. The luminal domain of LNPEP contains an aminopeptidase activity that is involved in peptide hormone processing and antigenic peptide processing. LNPEP is also a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to the GSVs.
Synonyms: Leucyl/cystinyl amino peptidase, insulin-responsive aminopeptidase, CAP, IRAP, PLAP, P-LAP, oxytocinase, otase, vasopressinase, angiotensin 4 receptor, gp160, vp160 - Molecular Weight
- 113 kDa
- Gene ID
- 4012
- NCBI Accession
- NP_005566
- Pathways
- Regulation of long-term Neuronal Synaptic Plasticity
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