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TNFRSF4 antibody

TNFRSF4 Reactivity: Mouse FACS, IF Host: Rat Monoclonal OX-86 unconjugated

Catalog No. ABIN1112435

Datasheet as PDF

Target See all TNFRSF4 Antibodies

TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
Reactivity
64

48

31

4

4

4

4

2

2

1

1
Mouse
Host
54

31

13

2
Rat
Compatible Secondaries
Clonality
53

45
Monoclonal
Conjugate
50

12

9

6

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This TNFRSF4 antibody is un-conjugated
Application
56

45

31

15

14

13

10

9

9

7

6

4

3

3

2

2

2

1

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF)

Characteristics

Monoclonal Anti-Mouse CD134 is recommended for use in flow cytometry for identification of CD134 also known as OX-40.

Immunogen

Recombinant mouse OX-40-CD4 chimeric protein Species

Clone

OX-86

Isotype

IgG1

Top Product

Discover our top product TNFRSF4 Primary Antibody
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-214) antibody
TNFRSF4 Reactivity: Human WB, FACS, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 3G5G7 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 59-205) antibody
TNFRSF4 Reactivity: Human, Chimpanzee FACS, ELISA, IHC, IF, Coat, ISt, StM Host: Mouse Monoclonal OX40-3108 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibody (PE)
TNFRSF4 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal Ber-ACT35 PE

anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibody (FITC)
TNFRSF4 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal Ber-ACT35 FITC

anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibody (APC)
TNFRSF4 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal Ber-ACT35 APC

anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-214) antibody
TNFRSF4 Reactivity: Human WB, FACS, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 2D1B8 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibody
TNFRSF4 Reactivity: Human, Non-Human Primate WB, FACS, ELISA, IP, IHC (fro), IHC (p) Host: Mouse Monoclonal Ber-ACT35 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 101-200) antibody
TNFRSF4 Reactivity: Human, Mouse, Rat WB, ELISA, IF (p), IHC (fro), IF (cc), ICC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-214) antibody
TNFRSF4 Reactivity: Human WB, FACS, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 7B5E10 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-216) antibody
TNFRSF4 Reactivity: Human FACS, ELISA Host: Rabbit Monoclonal DM116 unconjugated

Application Notes

It is recommended for use in flow cytometry. This reagent is effective for direct immunofluorescence staining of mouse tissue for flow cytometric analysis using 1 µg/10^6 cells

Comment

Purified, unconjugated.

Restrictions

For Research Use only
Format

Liquid

Buffer

The conjugate is provided in liquid form in buffer containing 1% bovine serum albumin (BSA) and 0,09% Sodium azide, pH 7.2.

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C
Target

TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Alternative Name

CD134 (TNFRSF4 Products)

Synonyms

TNFRSF4 antibody, ACT35 antibody, CD134 antibody, Ly-70 antibody, Ox40 antibody, TXGP1L antibody, Txgp1 antibody, OX40 antibody, TNF receptor superfamily member 4 antibody, tumor necrosis factor receptor superfamily, member 4 antibody, TNFRSF4 antibody, Tnfrsf4 antibody

Background

CD134 is a type I integral membrane protein also known as OX-40, ACT35, and tumor necrosis factor receptor superfamily member 4 (TNFRSF4). This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX-40 receptor binds to the OX-40 ligand (CD252) to provide a costimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, which implies that these interactions are important in the pathogenesis of some autoimmune diseases.

Pathways

Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints