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TNF alpha antibody
TNF alpha
Reactivity: Mouse
ICS
Host: Rat
Monoclonal
MP6-XT22
unconjugated
Product Details anti-TNF alpha Antibody
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Target
See all TNF alpha Antibodies
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Reactivity
All reactivities for TNF alpha antibodies
Mouse
Host
All hosts for TNF alpha antibodies
Rat
Clonality
All clonalities for TNF alpha antibodies
Monoclonal
Conjugate
All conjugates for TNF alpha antibodies
This TNF alpha antibody is un-conjugated
Application
All applications for TNF alpha antibodies
Intracellular Staining (ICS)
Brand
BD Pharmingen™
Purification
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Sterility
0.2 μm filtered
Endotoxin Level
Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen
Recombinant mouse TNF
Clone
MP6-XT22
Isotype
IgG1
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
Preservative
Azide free
Storage
4 °C
Storage Comment
Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
References for anti-TNF alpha antibody (ABIN1177296)
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Bitsaktsis, Winslow : "Fatal recall responses mediated by CD8 T cells during intracellular bacterial challenge infection. " in: Journal of immunology (Baltimore, Md. : 1950) , Vol. 177 , Issue 7 , pp. 4644-51 , (2006 ) (PubMed ).
Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver : "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. " in: Immunological reviews , Vol. 127 , Issue 9-10 , pp. 5-24 , (1992 ) (PubMed ).
Target Details for TNF alpha
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Target
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Alternative Name
TNF (TNF alpha Products )
Synonyms
DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, RATTNF antibody, Tnfa antibody, tnf antibody, TNF-a antibody, TNFalpha antibody, Tnfsf1a antibody, TNFa antibody, cTNF antibody, Tnf-alpha antibody, tnfa-like antibody, TNF-ALPHA antibody, dif antibody, tnfa antibody, xtnf antibody, tnfsf2 antibody, tnf-alpha antibody, Cachectin antibody, tumor necrosis factor antibody, tumor necrosis factor b (TNF superfamily, member 2) antibody, tumor necrosis factor alpha antibody, tumor necrosis factor a (TNF superfamily, member 2) antibody, TNF antibody, Tnf antibody, tnf antibody, tnfb antibody, tnf-alpha antibody, LOC103694380 antibody, tnfa antibody
Background
The MP6-XT22 antibody specificially binds to mouse Tumor Necrosis Factor (TNF, also known as TNF-alpha). The immunogen used to generate this hybridoma was recombinant mouse TNF. Synonyms: Tnf, Tnfa, TNF alpha, TNF-a, Tnfsf1a, Tnfsf2, TNFSF2, Cachectin, DIF
Pathways
NF-kappaB Signaling , Apoptosis , Caspase Cascade in Apoptosis , TLR Signaling , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Inflammasome
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