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TRKA antibody
NTRK1
Reactivity: Human, Mouse, Rat
WB, IHC (p), IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TRKA Antibody
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Target
See all TRKA (NTRK1) Antibodies
TRKA (NTRK1)
(Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
Reactivity
All reactivities for TRKA antibodies
Human, Mouse, Rat
Host
All hosts for TRKA antibodies
Rabbit
Clonality
All clonalities for TRKA antibodies
Polyclonal
Conjugate
All conjugates for TRKA antibodies
This TRKA antibody is un-conjugated
Application
All applications for TRKA antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
Specificity
The antibody detects 140 kDa TrkA. It does not cross-react with TrkB or TrkC.
Purification
Affinity Chromatography
Immunogen
Synthetic peptide surrounding amino acid 494 of human TrkA
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Discover our top product NTRK1 Primary Antibody
Alternatives
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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 725-821) antibody
NTRK1
Reactivity: Human, Mouse, Rat
WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (2nd Extracellular Domain), (AA 342-356) antibody
NTRK1
Reactivity: Human, Mouse, Rat
WB, IHC, IF, FACS, ICC, LCI
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Western blotting (0.5-4 μg/mL). Immunoprecipitation. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA, 0.01 % Thimerosal.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the antibody at -20 °C. For long-term storage, aliquot and freeze at -20 °C to -70 °C.
Target Details for TRKA
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Target
TRKA (NTRK1)
(Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
Alternative Name
TrkA (NTRK1 Products )
Synonyms
MTC antibody, TRK antibody, TRK1 antibody, TRKA antibody, Trk-A antibody, p140-TrkA antibody, CDHF12 antibody, CDHR16 antibody, HSCR1 antibody, MEN2A antibody, MEN2B antibody, MTC1 antibody, PTC antibody, RET-ELE1 antibody, RET51 antibody, Trk antibody, C80751 antibody, Tkr antibody, TrkA antibody, trk antibody, trka antibody, CTRKA antibody, trkA antibody, neurotrophic receptor tyrosine kinase 1 antibody, ret proto-oncogene antibody, neurotrophic tyrosine kinase, receptor, type 1 antibody, NTRK1 antibody, RET antibody, Ntrk1 antibody, ntrk1 antibody
Background
TrkA, the high affinity Nerve Growth Factor (NGF) receptor, autophosphorylates on tyrosine to activate multiple effectors. Phosphorylation at Tyr490 is required for Shc association and activation of the Ras-MAP kinase cascade. Residues Tyr674/675 lie within the catalytic domain, and phosphorylation at these sites reflects Trk kinase activity.Synonyms: High affinity nerve growth factor receptor, NTRK1, Neurotrophic tyrosine kinase receptor type 1, TRK, TRK1-transforming tyrosine kinase protein, Trk-A, p140-TrkA
Gene ID
4914
NCBI Accession
NP_001007793
UniProt
P04629
Pathways
RTK Signaling , Neurotrophin Signaling Pathway , cAMP Metabolic Process
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