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CD11b antibody (PE)

ITGAM Reactivity: Mouse FACS Host: Rat Monoclonal PE
Catalog No. ABIN133957
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 248
    • 155
    • 62
    • 33
    • 17
    • 17
    • 16
    • 14
    • 11
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    Mouse
    Host
    • 133
    • 99
    • 94
    • 2
    • 1
    • 1
    Rat
    Clonality
    • 234
    • 92
    • 1
    Monoclonal
    Conjugate
    • 107
    • 36
    • 29
    • 25
    • 20
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
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    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11b antibody is conjugated to PE
    Application
    • 248
    • 78
    • 74
    • 70
    • 55
    • 36
    • 36
    • 22
    • 20
    • 18
    • 13
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    • 7
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    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    Mouse CD11b (MAC-1, Ly 40)
    Purification
    Purified from ascitic fluid via Protein G Chromatography.
    Isotype
    IgG2b
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  • Restrictions
    For Research Use only
  • Concentration
    0.1 mg/ml
    Buffer
    R-PE conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from ascitic fluid via Protein G Chromatography)
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    CD11b (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background
    Anti-mouse CD11b (MAC-1) (Ly 40) monoclonal antibody is specific for the 170 kDa subunit of MAC-1, which mediates adhesion to ICAM-1 (CD54) and C3bi. Mac-1 is expressed on granulocytes, macrophages, natural killer cells, and B-1 cells in the peritoneal and pleural cavities. Mac-1 is up-regulated on neutrophils after activation. This particular clone blocks cell adherence and C3bi binding but does not block cell medited lysis (1,2,3,4,5,6). Applications include flow cytometry. This clone has been reported to be suitable for use in in vitro and in vivo blocking, immunohistochemistry (acetone-fixed frozen sections (1-20 µg/ml), immunoprecipitation and western blotting.
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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