Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MAP3K4 antibody (AA 1351-1450) (HRP)

MAP3K4 Reactivity: Human ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal HRP
Catalog No. ABIN1411784
  • Target See all MAP3K4 Antibodies
    MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))
    Binding Specificity
    • 14
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1351-1450
    Reactivity
    • 50
    • 8
    • 5
    Human
    Host
    • 47
    • 3
    Rabbit
    Clonality
    • 46
    • 4
    Polyclonal
    Conjugate
    • 21
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP3K4 antibody is conjugated to HRP
    Application
    • 30
    • 28
    • 23
    • 13
    • 13
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MAP3K4/MEK kinase-4
    Isotype
    IgG
    Top Product
    Discover our top product MAP3K4 Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))
    Alternative Name
    MAP3K4/MEK kinase-4 (MAP3K4 Products)
    Synonyms
    MAPKKK4 antibody, MEKK4 antibody, MTK1 antibody, PRO0412 antibody, D17Rp17 antibody, D17Rp17e antibody, MEKK 4 antibody, Mek4b antibody, Mekk4 antibody, RP17 antibody, Rp17a antibody, Tas antibody, mKIAA0213 antibody, mitogen activated protein kinase kinase kinase 4 antibody, mitogen-activated protein kinase kinase kinase 4 antibody, Map3k4 antibody, MAP3K4 antibody
    Background

    Synonyms: FLJ42439, KIAA0213, M3K4_HUMAN, MAP three kinase 1, MAP3K4, MAPK/ERK kinase kinase 4, MAPKKK4 antibodyMEK kinase 4, MEKK 4, MEKK4, Mitogen-activated protein kinase kinase kinase 4, MTK1, PRO0412, RP3-473J16.4

    Background: Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4, ASK 1 (MEK kinase-5) and MAP3K6 (MEK kinase-6). MEK kinase-1 has been shown to phosphorylate MEK-1 via Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK path-way. ASK1 activates both MEK-4 and MEK-3/MEK-6 pathways.

    Pathways
    MAPK Signaling
You are here:
Support