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IRS1 antibody (pSer612)
IRS1
Reactivity: Human, Mouse, Rat
WB, IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IRS1 Antibody
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Target
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IRS1
(Insulin Receptor Substrate 1 (IRS1))
Binding Specificity
All epitopes for IRS1 antibodies
pSer612
Reactivity
All reactivities for IRS1 antibodies
Human, Mouse, Rat
Host
All hosts for IRS1 antibodies
Rabbit
Clonality
All clonalities for IRS1 antibodies
Polyclonal
Conjugate
All conjugates for IRS1 antibodies
This IRS1 antibody is un-conjugated
Application
All applications for IRS1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Specificity
Epitopes for Species: H:S616,M:S612,R:S612
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 612 (P-M-SP-P-G).
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1 mg/mL
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Storage
-20 °C
Storage Comment
Store at -20°C / 1 year
Expiry Date
12 months
Target Details for IRS1
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Target
IRS1
(Insulin Receptor Substrate 1 (IRS1))
Alternative Name
IRS-1 (IRS1 Products )
Synonyms
HIRS-1 antibody, G972R antibody, IRS-1 antibody, IRS1IRM antibody, irs1 antibody, irsu antibody, IRS1 antibody, irs-1 antibody, irs1-a antibody, insulin receptor substrate 1 antibody, insulin receptor substrate 2 antibody, insulin receptor substrate 1 S homeolog antibody, IRS1 antibody, Irs1 antibody, irs2 antibody, irs1.S antibody
Background
IRS-1, IRS1, Insulin receptor substrate-1
UniProt
P35568
Pathways
Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Hormone Transport , Negative Regulation of Hormone Secretion , Response to Growth Hormone Stimulus , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process
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