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MEK1 antibody (pSer221, Ser217, Ser221)
MAP2K1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MEK1 Antibody
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Target
See all MEK1 (MAP2K1) Antibodies
MEK1 (MAP2K1)
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
Binding Specificity
All epitopes for MEK1 antibodies
pSer221, Ser217, Ser221
Reactivity
All reactivities for MEK1 antibodies
Human
Host
All hosts for MEK1 antibodies
Rabbit
Clonality
All clonalities for MEK1 antibodies
Polyclonal
Conjugate
All conjugates for MEK1 antibodies
This MEK1 antibody is un-conjugated
Application
All applications for MEK1 antibodies
Western Blotting (WB)
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Phosphorylated Antibodies
Immunogen
A phospho specific peptide corresponding to residues surrounding serine 217/221 of human MAP2K1/MAP2K2.
Isotype
IgG
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Discover our top product MAP2K1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:1000
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for MEK1
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Target
MEK1 (MAP2K1)
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
Alternative Name
MAP2K1/MAP2K2 (MAP2K1 Products )
Synonyms
Mek1 antibody, CFC3 antibody, MAPKK1 antibody, MEK1 antibody, MKK1 antibody, PRKMK1 antibody, MEKK1 antibody, Prkmk1 antibody, mek-2 antibody, si:ch211-242m18.2 antibody, wu:fj56a12 antibody, wu:fj61b01 antibody, zgc:56557 antibody, ATMEK1 antibody, F20B18.180 antibody, F20B18_180 antibody, MAP kinase/ ERK kinase 1 antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 antibody, NMAPKK antibody, MEK antibody, mitogen activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 L homeolog antibody, MAP kinase/ ERK kinase 1 antibody, Map2k1 antibody, MAP2K1 antibody, map2k1.L antibody, map2k1 antibody, MEK1 antibody
Background
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008],MEK1/MEK2,Protein phosphorylation,Protein phosphorylation,Protein phosphorylation,MAP2K1/MAP2K2
Molecular Weight
40 kDa/43 kDa/44 kDa
Gene ID
5604, 5605
UniProt
Q02750 , P36507
Pathways
MAPK Signaling , RTK Signaling , Interferon-gamma Pathway , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades , Autophagy , Signaling of Hepatocyte Growth Factor Receptor , BCR Signaling
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