PTP4A2 antibody (AA 58-162)
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- Target See all PTP4A2 Antibodies
- PTP4A2 (Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2))
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Binding Specificity
- AA 58-162
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PTP4A2 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human PTP4A2 (AA: 58-162) expressed in E. coli.
- Clone
- 5B6F4
- Isotype
- IgG2b
- Top Product
- Discover our top product PTP4A2 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Overexpression of the protein tyrosine phosphatase PRL-2 correlates with breast tumor formation and progression." in: Cancer research, Vol. 70, Issue 21, pp. 8959-67, (2010) (PubMed).
: "PRL-2 increases Epo and IL-3 responses in hematopoietic cells." in: Blood cells, molecules & diseases, Vol. 44, Issue 4, pp. 209-14, (2010) (PubMed).
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Overexpression of the protein tyrosine phosphatase PRL-2 correlates with breast tumor formation and progression." in: Cancer research, Vol. 70, Issue 21, pp. 8959-67, (2010) (PubMed).
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- Target
- PTP4A2 (Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2))
- Alternative Name
- PTP4A2 (PTP4A2 Products)
- Synonyms
- wu:fc05f09 antibody, wu:fi84b06 antibody, zgc:101724 antibody, MGC53390 antibody, MGC80084 antibody, MGC132077 antibody, PTP4A2 antibody, ptp4a2 antibody, Prl-2 antibody, HH13 antibody, HH7-2 antibody, HU-PP-1 antibody, OV-1 antibody, PRL-2 antibody, PRL2 antibody, PTP4A antibody, PTPCAAX2 antibody, ptp-IV1a antibody, ptp-IV1b antibody, protein tyrosine phosphatase type IVA, member 2b antibody, protein tyrosine phosphatase 4a2 antibody, protein tyrosine phosphatase type IVA, member 2 antibody, protein tyrosine phosphatase type IVA, member 2 L homeolog antibody, ptp4a2b antibody, ptp4a2 antibody, PTP4A2 antibody, ptp4a2.L antibody, Ptp4a2 antibody
- Background
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Description: The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. ,
Aliases: HH13, OV-1, PRL2, HH7-2, PRL-2, PTP4A, HU-PP-1, PTPCAAX2, ptp-IV1a, ptp-IV1b
- Molecular Weight
- 19.1 kDa
- Gene ID
- 8073
- HGNC
- 8073
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