wu:fc05f09 antibody, wu:fi84b06 antibody, zgc:101724 antibody, MGC53390 antibody, MGC80084 antibody, MGC132077 antibody, PTP4A2 antibody, ptp4a2 antibody, Prl-2 antibody, HH13 antibody, HH7-2 antibody, HU-PP-1 antibody, OV-1 antibody, PRL-2 antibody, PRL2 antibody, PTP4A antibody, PTPCAAX2 antibody, ptp-IV1a antibody, ptp-IV1b antibody, protein tyrosine phosphatase type IVA, member 2b antibody, protein tyrosine phosphatase 4a2 antibody, protein tyrosine phosphatase type IVA, member 2 antibody, protein tyrosine phosphatase type IVA, member 2 L homeolog antibody, ptp4a2b antibody, ptp4a2 antibody, PTP4A2 antibody, ptp4a2.L antibody, Ptp4a2 antibody
Background
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.,PTP4A2,HH13,HH7-2,HU-PP-1,OV-1,PRL-2,PRL2,PTP4A,PTPCAAX2,ptp-IV1a,ptp-IV1b,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,PTP4A2