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IRS1 antibody (pSer307)
IRS1
Reactivity: Human, Mouse, Rat
WB, IHC, IF/ICC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IRS1 Antibody
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Target
See all IRS1 Antibodies
IRS1
(Insulin Receptor Substrate 1 (IRS1))
Binding Specificity
All epitopes for IRS1 antibodies
pSer307
Reactivity
All reactivities for IRS1 antibodies
Human, Mouse, Rat
Host
All hosts for IRS1 antibodies
Rabbit
Clonality
All clonalities for IRS1 antibodies
Polyclonal
Conjugate
All conjugates for IRS1 antibodies
This IRS1 antibody is un-conjugated
Application
All applications for IRS1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)
Specificity
Phospho-IRS-1 (Ser307) Antibody detects endogenous levels of IRS-1 only when phosphorylated at Serine 307.
Purification
Immunogen affinity purified
Immunogen
A synthesized peptide derived from human IRS-1 around the phosphorylation site of Serine307.
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Discover our top product IRS1 Primary Antibody
Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Buffer
Phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage Comment
Stable for 12 months from date of receipt.
Expiry Date
12 months
Target Details for IRS1
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Target
IRS1
(Insulin Receptor Substrate 1 (IRS1))
Alternative Name
IRS-1 (IRS1 Products )
Synonyms
HIRS-1 antibody, G972R antibody, IRS-1 antibody, IRS1IRM antibody, irs1 antibody, irsu antibody, IRS1 antibody, irs-1 antibody, irs1-a antibody, insulin receptor substrate 1 antibody, insulin receptor substrate 2 antibody, insulin receptor substrate 1 S homeolog antibody, IRS1 antibody, Irs1 antibody, irs2 antibody, irs1.S antibody
Background
IRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2.
Molecular Weight
180 kDa
Pathways
Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Hormone Transport , Negative Regulation of Hormone Secretion , Response to Growth Hormone Stimulus , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process
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