MEK1 antibody (pThr286)
-
- Target See all MEK1 (MAP2K1) Antibodies
- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
-
Binding Specificity
- pThr286
-
Reactivity
- Human, Mouse, Rat, Cow, Rabbit, Pig, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This MEK1 antibody is un-conjugated
-
Application
- Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Proximity Ligation Assay (PLA)
- Specificity
- Region of human MAPK/ERK kinase 1 (dual specificity mitogen-activated protein kinase kinase 1) surrounding threonine 286 using the numbering given in entry NP_002746.1 (Gene ID 5604) when the threonine residue is phosphorylated.
- Purification
- Immunoaffinity purified
- Isotype
- IgG
- Top Product
- Discover our top product MAP2K1 Primary Antibody
-
-
- Application Notes
-
Approved: IF (1:500 - 1:2500), IHC, IHC-P (1:1000 - 1:5000), IP (2 - 10 μg/mg lysate), PLA (1:1000 - 1:20000)
Usage: Immunohistochemistry: Antigen retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Human controls: Breast Carcinoma, Colon Carcinoma, Lung Cancer, Ovarian Carcinoma, Prostate Carcinoma, Stomach Adenocarcinoma, Testicular Seminoma.
Not recommended for: WB - Comment
-
Target Species of Antibody: Human
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Tris-citrate/phosphate buffer, pH 7-8, 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C for up to 1 year.
- Expiry Date
- 12 months
-
- Target
- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
- Alternative Name
- MAP2K1 / MEK1 (MAP2K1 Products)
- Synonyms
- Mek1 antibody, CFC3 antibody, MAPKK1 antibody, MEK1 antibody, MKK1 antibody, PRKMK1 antibody, MEKK1 antibody, Prkmk1 antibody, mek-2 antibody, si:ch211-242m18.2 antibody, wu:fj56a12 antibody, wu:fj61b01 antibody, zgc:56557 antibody, ATMEK1 antibody, F20B18.180 antibody, F20B18_180 antibody, MAP kinase/ ERK kinase 1 antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 antibody, NMAPKK antibody, MEK antibody, mitogen activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 L homeolog antibody, MAP kinase/ ERK kinase 1 antibody, Map2k1 antibody, MAP2K1 antibody, map2k1.L antibody, map2k1 antibody, MEK1 antibody
- Background
-
Name/Gene ID: MAP2K1
Subfamily: MAP2K
Family: Protein Kinase
Synonyms: MAP2K1, ERK activator kinase 1, MAPK/ERK kinase 1, MAPKK 1, MKK1, PRKMK1, MEK 1, MAP kinase kinase 1, MAPKK1, MEK1 - Gene ID
- 5604
- Pathways
- MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
-