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Huntingtin antibody (AA 1844-2131)

HTT Reactivity: Rabbit WB, IHC, IP, IHC (fro) Host: Mouse Monoclonal unconjugated

Catalog No. ABIN201061

Datasheet as PDF

Target See all Huntingtin (HTT) Antibodies

Huntingtin (HTT)
Binding Specificity
15

6

4

4

4

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 1844-2131
Reactivity
64

46

37

5

3

2

2

1

1

1

1

1

1

1

1

1

1
Rabbit
Host
61

20

2
Mouse
Compatible Secondaries
Clonality
54

28
Monoclonal
Conjugate
55

3

3

3

3

3

3

3

1

1

1

1

1

1

1
This Huntingtin antibody is un-conjugated
Application
40

33

24

14

14

13

12

8

7

4

4

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity

Reacts with an epitope corresponding to the HDB region (amino acids 1844-2131) of the huntingtin protein. Clone 3H2240 detects a 350kD band on western blots but also detects smaller degradation products of huntingtin. The combined use of clone 3H2240, HDC8A4 and HDA3E10 demonstrate that huntingtin is enriched in neuronal cells in the brain.

Purification

Purified

Immunogen

Recombinant protein corresponding to amino acids 1844 - 2131 of huntingtin.

Type of Immunogen: Recombinant protein

Isotype

IgG1

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anti-Huntingtin (HTT) (AA 85-200) antibody
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anti-Huntingtin (HTT) (AA 81-190) antibody
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anti-Huntingtin (HTT) (AA 81-190) antibody
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anti-Huntingtin (HTT) (AA 782-920) antibody
HTT Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

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HTT Reactivity: Human IHC, ELISA Host: Rabbit Monoclonal 6F2 unconjugated Recombinant Antibody

anti-Huntingtin (HTT) antibody
HTT Reactivity: Human, Rat IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-Huntingtin (HTT) (AA 81-190) antibody
HTT Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3F9 unconjugated

anti-Huntingtin (HTT) (AA 416-424), (pSer421) antibody
HTT Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-Huntingtin (HTT) (AA 81-191) antibody
HTT Reactivity: Human WB, IHC, ELISA, IHC (p) Host: Mouse Monoclonal 3F1 unconjugated

Application Notes

Approved: IHC, IHC-Fr, IP, WB

Usage: Immunohistochemistry (frozen). Immunoprecipitation. Western Blot. Tested in IHC with frozen, acetone fixed rabbit brain.

Comment

Target Species of Antibody: Human

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

0.1 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target

Huntingtin (HTT)

Alternative Name

HTT / Huntingtin (HTT Products)

Synonyms

HTT antibody, hd antibody, ZHD antibody, CG9995 antibody, Dmel\\CG9995 antibody, HD antibody, Hsap\\HD antibody, Htt antibody, dHtt antibody, dhtt antibody, SLC6A4 antibody, huntington antibody, it15 antibody, htt antibody, IT15 antibody, AI256365 antibody, C430023I11Rik antibody, Hd antibody, Hdh antibody, huntingtin antibody, HTT antibody, htt antibody, LOC373520 antibody, Htt antibody

Background

Name/Gene ID: HTT
Family: Hungtintin

Synonyms: HTT, Huntingtin, Huntington disease protein, IT15, HD, HD protein

Gene ID

3064

UniProt

P42858

Pathways

PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport