PTPN11 antibody (N-Term)

Catalog No. ABIN220935

The Rabbit Polyclonal anti-PTPN11 antibody (ABIN220935) specifically detects PTPN11 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for PTPN11 antibody (N-Term) (ABIN220935)

Target: PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PTPN11 Antibody

Binding Specificity: N-Term

Specificity: Detects endogenous levels of SHP-2 independent of phosphorylation.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to residues surrounding the N-terminal domain of human SHP-2 (KLH coupled).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA, WB (1:1000)

Usage: Suitable for use in ELISA and Western Blot. Western Blot: 1:1000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, BSA, 50 % glycerol.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for PTPN11

Target: PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

Alternative Name: PTPN11 / SHP-2 / NS1

Background: Name/Gene ID: PTPN11
Subfamily: NT2
Family: Protein Phosphatase

Synonyms: PTPN11, Bptp-3, BPTP3, CFC, Csw, Corkscrew csw, Gene corkscrew, Phosphatase corkscrew, PTP-2C, SHP2, PTP-1D, PTP2C, SHP-2, SHPTP2, Noonan syndrome 1, SH-PTP2, SH-PTP3

Gene ID: 5781

UniProt: Q06124

Pathways: JAK-STAT Signaling, RTK Signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect