PTPN7 antibody
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- Target See all PTPN7 Antibodies
- PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PTPN7 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Homo sapiens protein tyrosine phosphatase, non-receptor type 7 (PTPN7), transcript variant 2
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human PTPN7(NP_542155) produced in HEK293T cell.
- Clone
- 3H8
- Isotype
- IgG1
- Top Product
- Discover our top product PTPN7 Primary Antibody
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- Application Notes
- WB 1:2000, IHC 1:150,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))
- Alternative Name
- PTPN7 (PTPN7 Products)
- Synonyms
- BPTP-4 antibody, HEPTP antibody, LC-PTP antibody, LPTP antibody, PTPNI antibody, C920001D21Rik antibody, Heptp antibody, Lcptp antibody, protein tyrosine phosphatase, non-receptor type 7 antibody, PTPN7 antibody, Ptpn7 antibody
- Background
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
- 44.8 kDa
- Gene ID
- 5778
- NCBI Accession
- NM_080588
- HGNC
- 5778
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