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TLR3 antibody (PE)

TLR3 Reactivity: Human FACS Host: Mouse Monoclonal TLR3-7 PE
Catalog No. ABIN2567451
  • Target See all TLR3 Antibodies
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Reactivity
    • 96
    • 63
    • 31
    • 6
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 84
    • 29
    • 3
    • 2
    Mouse
    Clonality
    • 87
    • 31
    Monoclonal
    Conjugate
    • 50
    • 18
    • 15
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR3 antibody is conjugated to PE
    Application
    • 81
    • 40
    • 37
    • 35
    • 23
    • 15
    • 13
    • 13
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Flow Cytometry (FACS)
    Specificity
    The TLR3.7 monoclonal antibody specifically reacts with human CD283 (TLR3), a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain.
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Clone
    TLR3-7
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TLR3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Storage
    4 °C
    Storage Comment
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Target
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Alternative Name
    CD283 (TLR3 Products)
    Synonyms
    CD283 antibody, IIAE2 antibody, AI957183 antibody, zgc:123006 antibody, toll like receptor 3 antibody, toll-like receptor 3 antibody, TLR3 antibody, Tlr3 antibody, tlr3 antibody
    Background
    The TLR3.7 monoclonal antibody specifically reacts with human CD283 (TLR3), a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. It is expressed by dendritic cells and recognize double-stranded RNA and polyinosine-polycytidylic acid. Upon ligand binding, CD283 induces type I interferon production and activation of the nuclear factor kappa-light-chain-enhancer of activated B cells complex (NF-κB).
    Gene ID
    7098
    UniProt
    O15455
    Pathways
    TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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