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CD4 antibody (PE)

CD4 Reactivity: Mouse FACS Host: Rat Monoclonal GK1-5 PE
Catalog No. ABIN2567639
  • Target See all CD4 Antibodies
    CD4
    Reactivity
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    • 183
    • 112
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    Mouse
    Host
    • 299
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    • 95
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    Rat
    Clonality
    • 399
    • 132
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    Monoclonal
    Conjugate
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    This CD4 antibody is conjugated to PE
    Application
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    Flow Cytometry (FACS)
    Specificity
    The GK1.5 monoclonal antibody specifically binds with the mouse CD4 Molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II.
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Clone
    GK1-5
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product CD4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Storage
    4 °C
    Storage Comment
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Target
    CD4
    Alternative Name
    CD4 (CD4 Products)
    Synonyms
    cd4 antibody, L3T4 antibody, Ly-4 antibody, CD4mut antibody, W3/25 antibody, p55 antibody, CD4 molecule antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, T-cell surface glycoprotein CD4 antibody, CD4 antigen antibody, Cd4 molecule antibody, CD4 antibody, LOC100125525 antibody, cd4 antibody, Cd4 antibody
    Background
    The GK1.5 monoclonal antibody specifically binds with the mouse CD4 Molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes, dendritic cells, pluripotent hematopoietic stem cells, B cell precursors, and lymphoid precursors inside the thymus. It is also expressed on the mouse egg cell membrane, enhancing adhesion to MHC class II bearing sperm. By interaction with MHC class II on the surface of APC, CD4 initiates the development of T lymphocytes and helps the optimum functioning of mature T lymphocytes. The binding of the GK1.5 antibody blocks the binding of the Anti-Mouse CD4 RM4-5 antibody.
    Gene ID
    12504
    UniProt
    P06332
    Pathways
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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