KCND2
Reactivity: Human
IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Western Blot: 1: 1000. Immunoprecipitation. Immunofluorescence. Positive Control: transfected HEK293 cells containing Kv4.2 cDNA. Negative control: untransfected HEK293 cells. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
PBS with 0,008 % sodium azide pH 7,4
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Target
KCND2
(Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 2 (KCND2))
In neurons voltage-dependent potassium channels are key determinants of the resting membrane potential and of membrane excitability, conditioning the frequency, and shape of action potential (1). Potassium channels are encoded by numerous genes whose products can be classified into distinct subfamilies of which the most distinctively characterized is that of the Kv1 shaker class (2) The rabbit anti Kv 4.2 potassium channel antibody recognizes an 80 kDa protein by western blot on rat hippocampal membranes and a protein of 80 kDa in lysates of HEK293 cells (3).Synonyms: KIAA1044, Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv4.2