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CD226 antibody (Alexa Fluor 647)
CD226
Reactivity: Mouse
FACS
Host: Rat
Monoclonal
TX42-1
Alexa Fluor 647
Product Details anti-CD226 Antibody (Alexa Fluor 647)
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Target
See all CD226 Antibodies
CD226
Reactivity
All reactivities for CD226 antibodies
Mouse
Host
All hosts for CD226 antibodies
Rat
Clonality
All clonalities for CD226 antibodies
Monoclonal
Conjugate
All conjugates for CD226 antibodies
This CD226 antibody is conjugated to Alexa Fluor 647
Application
All applications for CD226 antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
TX42-1
Isotype
IgG2a
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Discover our top product CD226 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for CD226
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Target
CD226
Alternative Name
CD226 (CD226 Products )
Synonyms
CD226 antibody, cd226 antibody, zgc:158817 antibody, BC051526 antibody, DNAM-1 antibody, DNAM1 antibody, Pta1 antibody, TLiSA1 antibody, PTA1 antibody, CD226 molecule antibody, CD226 antigen antibody, CD226 antibody, cd226 antibody, Cd226 antibody
Background
Mouse CD226 (DNAM-1) is a 65 kd glycoprotein of a member of Ig super-family adhesion molecule containing 2 immunoglobulin-like domains. It is associated with leukocyte function associated antigen-1 (LFA-1) involving in TCR-mediated signal transduction for T cell proliferation and differentiation. CD226 is also involved in NK cell and T cell mediated cytotoxicity against certain tumors. CD226 (DNAM-1) is constitutively expressed on naive CD8+ and CD4+ T cells, macrophages, and NK cells. It was reported that CD226 expression is up-regulated on Th1 cells, but down-regulated on Th2 and Th0 cells. CD155 and CD112 are the ligands for CD226.
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Cancer Immune Checkpoints
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