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TNFRSF4 antibody (Biotin)

TNFRSF4 Reactivity: Mouse FACS, ELISA, BR Host: Rat Monoclonal OX-86 Biotin
Catalog No. ABIN2660937
  • Target See all TNFRSF4 Antibodies
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    Reactivity
    • 64
    • 48
    • 31
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Mouse
    Host
    • 54
    • 31
    • 13
    • 2
    Rat
    Clonality
    • 53
    • 45
    Monoclonal
    Conjugate
    • 50
    • 12
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF4 antibody is conjugated to Biotin
    Application
    • 56
    • 45
    • 31
    • 15
    • 14
    • 13
    • 10
    • 9
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Blocking Reagent (BR)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    Clone
    OX-86
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TNFRSF4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    Alternative Name
    CD134 (TNFRSF4 Products)
    Synonyms
    TNFRSF4 antibody, ACT35 antibody, CD134 antibody, Ly-70 antibody, Ox40 antibody, TXGP1L antibody, Txgp1 antibody, OX40 antibody, TNF receptor superfamily member 4 antibody, tumor necrosis factor receptor superfamily, member 4 antibody, TNFRSF4 antibody, Tnfrsf4 antibody
    Background
    CD134 is a type I integral membrane protein also known as OX-40, ACT35, and tumor necrosis factor receptor superfamily member 4 (TNFRSF4). This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX-40 receptor binds to the OX-40 ligand (CD252) to provide a costimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, which implies that these interactions are important in the pathogenesis of some autoimmune diseases.
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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