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beta-2 Microglobulin antibody (FITC)
B2M
Reactivity: Human
FACS
Host: Mouse
Monoclonal
2M2
FITC
Product Details anti-beta-2 Microglobulin Antibody (FITC)
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Target
See all beta-2 Microglobulin (B2M) Antibodies
beta-2 Microglobulin (B2M)
(beta-2-Microglobulin (B2M))
Reactivity
All reactivities for beta-2 Microglobulin antibodies
Human
Host
All hosts for beta-2 Microglobulin antibodies
Mouse
Clonality
All clonalities for beta-2 Microglobulin antibodies
Monoclonal
Conjugate
All conjugates for beta-2 Microglobulin antibodies
This beta-2 Microglobulin antibody is conjugated to FITC
Application
All applications for beta-2 Microglobulin antibodies
Flow Cytometry (FACS)
Cross-Reactivity
Pig (Porcine)
Purification
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone
2M2
Isotype
IgG1 kappa
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Discover our top product B2M Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for beta-2 Microglobulin
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Target
beta-2 Microglobulin (B2M)
(beta-2-Microglobulin (B2M))
Alternative Name
Beta2-Microglobulin (B2M Products )
Synonyms
Ly-m11 antibody, beta2-m antibody, beta2m antibody, bwm antibody, wu:fa94c05 antibody, wu:fb10a09 antibody, b2m-W01 antibody, b2m-W03 antibody, b2m-Z01 antibody, b2m-Z02 antibody, b2m-Z03 antibody, B2M antibody, b2m antibody, B2MG antibody, wu:fb66f11 antibody, wu:fj01f08 antibody, zgc:64161 antibody, b-2-m antibody, beta-2-microglobulin antibody, beta-2 microglobulin antibody, beta-2-microglobulin S homeolog antibody, beta-2-microglobulin, like antibody, B2M antibody, B2m antibody, b2m antibody, b2m.S antibody, b2ml antibody
Background
β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+ T cells.
Pathways
TCR Signaling , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process
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