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H2AFX antibody (pSer139) (FITC)

H2AFX Reactivity: Human, Mouse FACS Host: Mouse Monoclonal 2F3 FITC
Catalog No. ABIN2661907
  • Target See all H2AFX Antibodies
    H2AFX (H2A Histone Family, Member X (H2AFX))
    Binding Specificity
    • 44
    • 27
    • 18
    • 11
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer139
    Reactivity
    • 184
    • 85
    • 60
    • 26
    • 26
    • 20
    • 17
    • 12
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 163
    • 21
    • 2
    Mouse
    Clonality
    • 128
    • 58
    Monoclonal
    Conjugate
    • 122
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This H2AFX antibody is conjugated to FITC
    Application
    • 147
    • 53
    • 51
    • 43
    • 37
    • 27
    • 25
    • 24
    • 16
    • 12
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    Clone
    2F3
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product H2AFX Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    H2AFX (H2A Histone Family, Member X (H2AFX))
    Alternative Name
    H2A.X (H2AFX Products)
    Synonyms
    H2A.X antibody, H2A/X antibody, H2AX antibody, AW228881 antibody, H2ax antibody, Hist5-2ax antibody, gammaH2ax antibody, zgc:56329 antibody, h2a.x antibody, h2a/x antibody, h2ax antibody, RGD1566119 antibody, h2a antibody, h2afx antibody, H2A histone family member X antibody, H2A histone family, member X antibody, H2A histone family member X L homeolog antibody, histone cluster 1, H2ah antibody, histone cluster 2, H2ab S homeolog antibody, histone H2AX antibody, H2AFX antibody, H2afx antibody, h2afx antibody, h2afx.L antibody, HIST1H2AH antibody, hist2h2ab.S antibody, LOC100522201 antibody, LOC100720536 antibody
    Background
    H2A.X is a 14 kD basal histone and a member of the H2 histone family. This nuclear protein is synthesized in the G1 and S phase of the cell cycle and is known to be important for recombination between immunoglobulin switch regions. H2A.X becomes phosphorylated on serine 139 after double-stranded DNA breaks. Phosphorylated H2A.X promotes DNA repair and maintains genomic stability. The 2F3 monoclonal antibody reacts with phosphorylated human H2A.X (Ser139) and has been shown to be useful for Western blotting and immunofluorescence.
    Pathways
    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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