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CD226 antibody (PE)

CD226 Reactivity: Mouse WB, FACS, IHC, IP, ICC Host: Rat Monoclonal 10E5 PE
Catalog No. ABIN2663192
  • Target See all CD226 Antibodies
    CD226
    Reactivity
    • 68
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    Mouse
    Host
    • 51
    • 19
    • 3
    Rat
    Clonality
    • 47
    • 25
    • 1
    Monoclonal
    Conjugate
    • 43
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD226 antibody is conjugated to PE
    Application
    • 40
    • 30
    • 25
    • 13
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    10E5
    Isotype
    IgG2b, IgG2b kappa
    Top Product
    Discover our top product CD226 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD226
    Alternative Name
    CD226 (CD226 Products)
    Synonyms
    CD226 antibody, cd226 antibody, zgc:158817 antibody, BC051526 antibody, DNAM-1 antibody, DNAM1 antibody, Pta1 antibody, TLiSA1 antibody, PTA1 antibody, CD226 molecule antibody, CD226 antigen antibody, CD226 antibody, cd226 antibody, Cd226 antibody
    Background
    CD226 (DNAM-1) is constitutively expressed on native CD8+ cells and on CD4+ T cells,macrophages and NK cells.This antibody (10E5) was reported to bind about 40 % of inactivated CD4+ cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It is also reported to suppress antigen-specific T cell expansion and EAE(experimental allergic encephalitis) mediated by Th1 cells.
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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