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SWAP70 antibody
SWAP70
Reactivity: Human
BCA
Host: Mouse
Monoclonal
9D9A19
unconjugated
Product Details anti-SWAP70 Antibody
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Target
See all SWAP70 Antibodies
SWAP70
(SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
Reactivity
All reactivities for SWAP70 antibodies
Human
Host
All hosts for SWAP70 antibodies
Mouse
Clonality
All clonalities for SWAP70 antibodies
Monoclonal
Conjugate
All conjugates for SWAP70 antibodies
This SWAP70 antibody is un-conjugated
Application
All applications for SWAP70 antibodies
Biochemical Assay (BCA)
Purification
Affinity purified.
Clone
9D9A19
Isotype
IgG1 kappa
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Discover our top product SWAP70 Primary Antibody
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
phosphate-buffered solution, pH 7.2, containing 0.05 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Upon receipt, store undiluted between 2°C and 8°C.
Target Details for SWAP70
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Target
SWAP70
(SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
Alternative Name
SWAP70 (SWAP70 Products )
Synonyms
SWAP-70 antibody, 70kDa antibody, AV235546 antibody, HSPC321 antibody, swap70b antibody, zgc:63599 antibody, switching B-cell complex subunit SWAP70 antibody, SWA-70 protein antibody, SWAP switching B-cell complex 70 antibody, SWAP switching B-cell complex 70kDa subunit antibody, switching B-cell complex subunit SWAP70a antibody, SWAP70 antibody, Swap70 antibody, swap70 antibody, swap70a antibody
Background
SWAP70 was initially isolated as a component of an isotype switch recombination complex (SWAP) from activated B lymphocytes. It translocates from cytoplasm to the nucleus upon B cell activation. SWAP70 interacts with F-actin and RAC, binds to PI(3,4)P2, and regulates membrane ruffling and lamellipodia formation in response to growth factor stimulation.
Pathways
Production of Molecular Mediator of Immune Response
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