HOXA1 antibody
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- Target See all HOXA1 Antibodies
- HOXA1 (Homeobox A1 (HOXA1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HOXA1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects endogenous levels of Hox-A1 protein. (region surrounding Gln203)
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Purity
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product HOXA1 Primary Antibody
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- Application Notes
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- DO NOT FREEZE!
- Storage
- 4 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C.
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- Target
- HOXA1 (Homeobox A1 (HOXA1))
- Alternative Name
- HOXA1 / HOX1F (HOXA1 Products)
- Synonyms
- BSAS antibody, HOX1 antibody, HOX1F antibody, bsas antibody, hox1f antibody, xhoxa1 antibody, hoxa1-A antibody, Xhox.lab antibody, xhox.lab2 antibody, HOXA1 antibody, hox1 antibody, MGC79507 antibody, ERA1 antibody, Hox-1.6 antibody, Xhox.lab2 antibody, hoxa1 antibody, homeobox A1 antibody, homeobox A1 L homeolog antibody, homeobox A1 S homeolog antibody, homeo box A1 antibody, HOXA1 antibody, hoxa1.L antibody, hoxa1 antibody, Hoxa1 antibody, hoxa1.S antibody
- Background
- Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxA1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor which has been shown to play important roles in cell differentiation and embryogenesis. HoxA1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, HoxA2 is expressed in the mesenchyme and epithelial cells of the palate, however its expression is restricted to the tips of the growing palatal shelves. HoxA2 protein is predominantly expressed in the nuclei of cells in the ventral mantle region of the developing embryo. In the developing and adult mouse spinal cord, HoxA2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. HoxA7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. HoxA7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.Synonyms: Homeobox protein Hox-1F, Homeobox protein Hox-A1
- Molecular Weight
- approx. 37 kDa
- Gene ID
- 3198
- NCBI Accession
- NP_005513
- UniProt
- P49639
- Pathways
- Sensory Perception of Sound
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