AES antibody (C-Term)
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- Target See all AES Antibodies
- AES (Amino-terminal Enhancer of Split (AES))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AES antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GLQPPSLPAV SAGTGLLSLS ALGSQAHLSK EDKNGHDGDT HQEDDGEKSD
- Predicted Reactivity
- Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against AES. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human AES
- Top Product
- Discover our top product AES Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 197 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- AES (Amino-terminal Enhancer of Split (AES))
- Alternative Name
- AES (AES Products)
- Synonyms
- AES-1 antibody, AES-2 antibody, ESP1 antibody, GRG antibody, GRG5 antibody, TLE5 antibody, AL024115 antibody, Esp1 antibody, Grg antibody, Grg-5 antibody, Grg5 antibody, Tle5 antibody, zgc:64216 antibody, aes-1 antibody, aes-2 antibody, esp1 antibody, grg antibody, grg5 antibody, tle5 antibody, xgrg-5 antibody, AES antibody, amino-terminal enhancer of split antibody, amino-terminal enhancer of split S homeolog antibody, AES antibody, Aes antibody, aes antibody, aes.S antibody
- Background
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AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genesThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AES-1, AES-2, ESP1, GRG, GRG5, TLE5
Protein Interaction Partner: MFAP1, MBNL1, SMAD3, LMO2, LMO1, KRT31, DDX6, CRX, BYSL, BCL6, AES, AEN, CARD9, PARVG, LSM2, HOMEZ, MAGOHB, RNF31, VPS37C, C1orf109, OSGIN1, MED4, PRPF31, GORASP2, KANK2, LDOC1, MTUS2, DIP2A, NCDN, BAHD1, IKZF3, U2AF2, RBPMS, FRS3, NEK6, CALCOCO2, ABI2, T
Protein Size: 197 - Molecular Weight
- 22 kDa
- Gene ID
- 166
- NCBI Accession
- NM_001130, NP_001121
- UniProt
- Q08117
- Pathways
- WNT Signaling, SARS-CoV-2 Protein Interactome
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