FOXO1 antibody (N-Term)
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- Target See all FOXO1 Antibodies
- FOXO1 (Forkhead Box O1 (FOXO1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Pig, Dog, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FOXO1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MAEAPQVVEI DPDFEPLPRP RSCTWPLPRP EFSQSNSATS SPAPSGSAAA
- Predicted Reactivity
- Cow: 92%, Dog: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rat: 85%, Yeast: 85%
- Characteristics
- This is a rabbit polyclonal antibody against FOXO1A. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human FOXO1A
- Top Product
- Discover our top product FOXO1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 655 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees." in: Biogerontology, Vol. 15, Issue 4, pp. 389-400, (2014) (PubMed).
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Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees." in: Biogerontology, Vol. 15, Issue 4, pp. 389-400, (2014) (PubMed).
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- Target
- FOXO1 (Forkhead Box O1 (FOXO1))
- Alternative Name
- FOXO1A (FOXO1 Products)
- Synonyms
- FKH1 antibody, FKHR antibody, FOXO1A antibody, FoxO1a.1 antibody, foxo1 antibody, zgc:153388 antibody, Fkhr antibody, Foxo1a antibody, AI876417 antibody, Afxh antibody, Fkhr1 antibody, fkh1 antibody, fkhr antibody, foxo1a antibody, xFoxO1 antibody, FoxO1A antibody, foxo1a.2 antibody, forkhead box O1 antibody, forkhead box O1 a antibody, forkhead box O1 L homeolog antibody, forkhead box O1 b antibody, FOXO1 antibody, foxo1a antibody, Foxo1 antibody, foxo1 antibody, foxo1.L antibody, foxo1b antibody
- Background
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FOXO1A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of FOXO1A has not yet been determined, however, it may play a role in myogenic growth and differentiation. Translocation of FOXO1A gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
Alias Symbols: FKH1, FKHR, FOXO1A
Protein Interaction Partner: EP300, AKT1, MST1, SIRT1, FHL2, ATG7, IRF3, FSHR, ESR1, Ubc, TXNRD1, RARA, MDM2, NLK, SKP2, SIRT2, STUB1, CREBBP, PML, LRPPRC, HOXA11, HNF4A, PARP1, DYRK1A, THRB, CSNK1G1, YWHAG, GSK3B, SMAD3, PAK1, PPARG, YWHAZ, SMAD4, AR, G6PC, SRC, CEBPB, FOXG1, HOXA10
Protein Size: 655 - Molecular Weight
- 70 kDa
- Gene ID
- 2308
- NCBI Accession
- NM_002015, NP_002006
- UniProt
- Q12778
- Pathways
- PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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