POLD2 antibody (N-Term)
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- Target See all POLD2 Antibodies
- POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse, Rabbit, Cow, Guinea Pig, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLD2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LREVSEEHNL LPQPPRSKYI HPDDELVLED ELQRIKLKGT IDVSKLVTGT
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against POLD2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human POLD2
- Top Product
- Discover our top product POLD2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 469 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))
- Alternative Name
- POLD2 (POLD2 Products)
- Synonyms
- 50kDa antibody, p50 antibody, po1D2 antibody, cdc1 antibody, si:dz150f13.3 antibody, zgc:55633 antibody, zgc:77043 antibody, DNA polymerase delta 2, accessory subunit antibody, polymerase (DNA directed), delta 2, regulatory subunit antibody, polymerase (DNA directed), delta 2, accessory subunit L homeolog antibody, POLD2 antibody, Pold2 antibody, pold2.L antibody, pold2 antibody
- Background
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This protein is a DNA polymerase delta complex ,it involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen, the multisubunit replication factor C, and the 4 subunit polymerase complex: POLD1, POLD2, POLD3, and POLD4The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA, MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1 (MIM 174761), POLD2, POLD3 (MIM 611415), and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]).[supplied by OMIM].
Alias Symbols: -
Protein Interaction Partner: UBC, SPRTN, FOXK1, FAM129A, XRN1, POLD1, MMS19, POLD4, CCHCR1, SOX12, EP300, UBD, BBLF2-BBLF3, POLD3, PCNA, POLDIP3, POLDIP2, KCTD13, WRNIP1, LSM6, WRN, CDK2, CDKN1A,
Protein Size: 469 - Molecular Weight
- 51 kDa
- Gene ID
- 5425
- NCBI Accession
- NM_006230, NP_006221
- UniProt
- P49005
- Pathways
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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