IL1R1 antibody (C-Term)
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- Target See all IL1R1 Antibodies
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Horse, Guinea Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL1R1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LELEKIQDYE KMPESIKFIK QKHGAIRWSG DFTQGPQSAK TRFWKNVRYH
- Predicted Reactivity
- Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against IL1R1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product IL1R1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 569 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Alternative Name
- IL1R1 (IL1R1 Products)
- Synonyms
- CD121A antibody, D2S1473 antibody, IL-1R-alpha antibody, IL1R antibody, IL1RA antibody, P80 antibody, CD121a antibody, CD121b antibody, IL-iR antibody, Il1r-1 antibody, DER4 antibody, Fit-1 antibody, Ly84 antibody, ST2L antibody, St2 antibody, St2-rs1 antibody, T1 antibody, T1/ST2 antibody, interleukin 1 receptor type 1 antibody, interleukin 1 receptor, type I antibody, interleukin 1 receptor-like 1 antibody, IL1R1 antibody, Il1r1 antibody, Il1rl1 antibody
- Background
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The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
Alias Symbols: CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80
Protein Interaction Partner: TRAF6, IRAK1, IL1RAP, MYD88, HERPUD1, TICAM2, PELI1, IRAK2, MARCH8, IRAK4, TOLLIP, TOM1, UBC, IL1F10, SIGIRR, PIK3R1, IL1A, IL1B, IL1RN,
Protein Size: 569 - Molecular Weight
- 63 kDa
- Gene ID
- 3554
- NCBI Accession
- NM_000877, NP_000868
- UniProt
- P14778
- Pathways
- NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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