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GZMB antibody (C-Term)

GZMB Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB19353 unconjugated
Catalog No. ABIN2840855
  • Target See all GZMB Antibodies
    GZMB (Granzyme B (GZMB))
    Binding Specificity
    • 18
    • 16
    • 13
    • 10
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 175-203, C-Term
    Reactivity
    • 120
    • 49
    • 24
    • 10
    • 4
    • 2
    • 1
    • 1
    Human
    Host
    • 80
    • 43
    • 1
    Rabbit
    Clonality
    • 76
    • 48
    Polyclonal
    Conjugate
    • 78
    • 11
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GZMB antibody is un-conjugated
    Application
    • 71
    • 42
    • 37
    • 37
    • 19
    • 18
    • 18
    • 14
    • 13
    • 10
    • 9
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This GZMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-203 amino acids from the C-terminal region of human GZMB.
    Clone
    RB19353
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GZMB Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    GZMB (Granzyme B (GZMB))
    Alternative Name
    GZMB (GZMB Products)
    Synonyms
    CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
    Background
    Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
    Molecular Weight
    27716
    Gene ID
    3002
    NCBI Accession
    NP_004122
    UniProt
    P10144
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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