c-MET antibody (Catalytic Domain)

Catalog No. ABIN317487

The Mouse Monoclonal anti-c-MET antibody (Clone 4AT44) (ABIN317487) specifically detects c-MET in WB and EIA. The antibody is reactive with Human and Mouse samples.

Quick Overview for c-MET antibody (Catalytic Domain) (ABIN317487)

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This c-MET antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 4AT44

Product Details anti-c-MET Antibody

Binding Specificity: Catalytic Domain

Specificity: This antibody recognises c-Met.

Characteristics: Synonyms: Hepatocyte growth factor receptor, MET, Scatter factor receptor, HGF/SF receptor, c-Met,Met proto-oncogene tyrosine kinase

Purification: Affinity Chromatography on Protein G

Immunogen: Purified recombinant protein representing the catalytic domain of human Met/HGFR

Isotype: IgG1

Application Details

Application Notes: Western blot: 1: 100 - 1: 500. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C forlonger. Avoid repeated freezing and thawing. Should this product contain a precipitate werecommend microcentrifugation before use.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for c-MET

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Alternative Name: HGF Receptor

Background: C-Met is a receptor tyrosine kinase also known as Hepatocyte growth factor receptor or HGFR. Binding HGF leads to autophosphorylation of c-Met and the activation of signal transduction pathways.Synonyms: HGF/SF receptor, Hepatocyte growth factor receptor, MET, Met proto-oncogene tyrosine kinase, Scatter factor receptor, c-Met

Gene ID: 4233

UniProt: P08581

Pathways: RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor