You are viewing an incomplete version of our website. Please click to reload the website as full version.

KIT antibody (Mast/stem Cell Growth Factor Receptor) (PE)

Details for Product anti-KIT Antibody No. ABIN319617, Supplier: Log in to see
Antigen
  • Bs
  • CD117
  • Fdc
  • Gsfsco1
  • Gsfsco5
  • Gsfsow3
  • SCO1
  • SCO5
  • SOW3
  • Ssm
  • Tr-kit
  • W
  • c-KIT
  • C-Kit
  • PBT
  • SCFR
  • MGF
  • c-kit
  • kit oncogene
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Kit
  • KIT
Alternatives
anti-Mouse (Murine) KIT antibody for Flow Cytometry
Reactivity
Mouse (Murine)
911
478
159
31
30
27
19
13
12
5
5
4
4
2
Host
Rat
665
297
231
8
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This KIT antibody is conjugated to PE
111
88
88
65
49
39
20
16
15
11
10
10
10
9
9
8
8
8
8
8
5
5
5
5
5
5
5
4
4
3
3
3
3
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS)
443
398
383
190
178
150
105
95
76
50
25
13
13
10
9
8
5
5
4
4
4
3
2
2
2
2
2
2
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Immunogen IL-3 dependent mast cells. Spleen cells from immunised Wistar rats were fused with cells of the Fox-NY mouse myeloma cell line.
Clone 2B8
Isotype IgG2b
Specificity This antibody reacts with CD117 also known as Kit or c-kit receptor. Clone 2B8 recognises an epitope within the extracellular region of CD117.
Purification Purified IgG prepared by affinity chromatography on Protein A.
Alternative Name CD117 / C-Kit (KIT Antibody Abstract)
Background CD117 is the receptor of the steel factor (Stem Cell Factor). C-kit receptor is expressed on 5-10 % of total adult bone marrow cells including multipotent hematopoietic cells.Synonyms: KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase, SCFR
Gene ID 16590
NCBI Accession NP_066922
UniProt P05532
Research Area CD Antigens, Surface Receptors of Immune Cells, Growth Factors, Receptors, Proliferation Markers
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance
Application Notes Flow Cytometry: Use 10 μL of neat antibody to label 10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Reconstitution Restore with distilled water.
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice This product is photosensitive and should be protected from light
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Background publications Fleming, Alpern, Uchida, Ikuta, Weissman: "Steel factor influences the distribution and activity of murine hematopoietic stem cells in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 8, pp. 3760-4, 1993 (PubMed).

Ikuta, Weissman: "Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 4, pp. 1502-6, 1992 (PubMed).