FOXO1 antibody (AA 242-655)

Catalog No. ABIN342252

Product Details anti-FOXO1 Antibody

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Binding Specificity: AA 242-655

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXO1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Recognizes human FKHR (ForkHead in Rhabdomyosarcoma), a 70 kD protein which is a member of a subfamily of the forkhead homeotic gene family of transcription factors. Recent studies have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C-terminus of the FKHR protein.

Purification: Protein G purified

Immunogen: GST fusion protein containing the region encoding aa 242-655 of human FKHR expressed in E. coli.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Approved: WB (0.1 - 2 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4

Handling Advice: Avoid freeze/thaw cycles.

Storage: -80 °C

Storage Comment: Store at -70°C, avoid freeze/thaw cycles.

Target Details for FOXO1

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Alternative Name: FOXO1 / FKHR (FOXO1 Products)

Synonyms: FKH1 antibody, FKHR antibody, FOXO1A antibody, FoxO1a.1 antibody, foxo1 antibody, zgc:153388 antibody, Fkhr antibody, Foxo1a antibody, AI876417 antibody, Afxh antibody, Fkhr1 antibody, fkh1 antibody, fkhr antibody, foxo1a antibody, xFoxO1 antibody, FoxO1A antibody, foxo1a.2 antibody, forkhead box O1 antibody, forkhead box O1 a antibody, forkhead box O1 L homeolog antibody, forkhead box O1 b antibody, FOXO1 antibody, foxo1a antibody, Foxo1 antibody, foxo1 antibody, foxo1.L antibody, foxo1b antibody

Background: Name/Gene ID: FOXO1
Family: Transcription factor

Synonyms: FOXO1, FKHR, Forkhead in rhabdomyosarcoma, FOXO1A, FKH1, Forkhead box protein O1, Forkhead box protein O1A, Forkhead box O1, Forkhead box o1a, Forkhead domain protein fkhr

Gene ID: 2308

UniProt: Q12778

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling