CYP19A1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target
Aromatase (CYP19A1)
(Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
ARO antibody, ARO1 antibody, CPV1 antibody, CYAR antibody, CYP19 antibody, CYPXIX antibody, P-450AROM antibody, Aromatase antibody, Cyp19 antibody, Cyp19a antibody, p450arom antibody, P450 arom antibody, aro antibody, cyp19 antibody, cyp19a antibody, p450arom-A antibody, P450AROM antibody, Ar antibody, ArKO antibody, Int-5 antibody, Int5 antibody, CYP19P1 antibody, CYP19A1 antibody, CYP19a1 antibody, P450aromA antibody, ar1 antibody, cypXIX antibody, etID309862.18 antibody, zgc:136541 antibody, AroB antibody, CYP19a2 antibody, P450aromB antibody, cyp19b antibody, zgc:92614 antibody, cyp19a1 antibody, cytochrome P450 family 19 subfamily A member 1 antibody, cytochrome P450, family 19, subfamily a, polypeptide 1 antibody, cytochrome P450 family 19 subfamily A member 1 L homeolog antibody, aromatase antibody, cytochrome P450 aromatase antibody, cytochrome P450, family 19, subfamily A, polypeptide 1 antibody, cytochrome P450 19A1 antibody, cytochrome P450, family 17, subfamily A, polypeptide 1 antibody, cytochrome P450, family 19 antibody, cytochrome P450, family 19, subfamily A, polypeptide 1a antibody, cytochrome P450, family 19, subfamily A, polypeptide 1b antibody, cytochrome P450 19A1-like antibody, CYP19A1 antibody, Cyp19a1 antibody, cyp19a1.L antibody, SAV_2383 antibody, pfcyp19b-tstr antibody, CYP19 antibody, cyp19a1a antibody, cyp19a1b antibody, LOC101174651 antibody
Background
CYP19A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity, the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.Synonyms: ARO1, CYAR, CYP19, CYP19A1, CYPXIX, Cytochrome P450 19A1, Estrogen synthetase, P450AROM