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CDK6 antibody (pTyr13)
CDK6
Reactivity: Human, Mouse
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CDK6 Antibody
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Target
See all CDK6 Antibodies
CDK6
(Cyclin-Dependent Kinase 6 (CDK6))
Binding Specificity
All epitopes for CDK6 antibodies
pTyr13
Reactivity
All reactivities for CDK6 antibodies
Human, Mouse
Host
All hosts for CDK6 antibodies
Rabbit
Clonality
All clonalities for CDK6 antibodies
Polyclonal
Conjugate
All conjugates for CDK6 antibodies
This CDK6 antibody is un-conjugated
Application
All applications for CDK6 antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificity
The antibody detects endogenous level of CDK6 only when phosphorylated at tyrosine 13.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen
Peptide sequence around phosphorylation site of pTyr13 (Q-Q-Y (p) -E-C) derived from Human CDK6. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100 Immunofluorescence: 1:100-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for CDK6
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Target
CDK6
(Cyclin-Dependent Kinase 6 (CDK6))
Alternative Name
CDK6 (CDK6 Products )
Synonyms
CDK6 antibody, PLSTIRE antibody, 5830411I20 antibody, AI504062 antibody, Crk2 antibody, cyclin dependent kinase 6 antibody, cyclin-dependent kinase 6 antibody, CDK6 antibody, Cdk6 antibody
Background
Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins.
Molecular Weight
36 kDa
NCBI Accession
NP_001138
UniProt
Q00534
Pathways
Cell Division Cycle , Mitotic G1-G1/S Phases
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