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MYBL2 antibody (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2) (C-Term)

Details for Product anti-MYBL2 Antibody No. ABIN374731, Supplier: Log in to see
Antigen
  • MYBL2
  • bmyb
  • b-myb
  • B-Myb
  • Bmyb
  • B-MYB
  • BMYB
  • myb1
  • v-myb myeloblastosis viral oncogene homolog (avian)-like 2
  • v-myb myeloblastosis viral oncogene homolog-like 2
  • myeloblastosis oncogene-like 2
  • v-myb avian myeloblastosis viral oncogene homolog-like 2
  • MYBL2
  • mybl2
  • Mybl2
Alternatives
anti-Human MYBL2 antibody for Immunocytochemistry
Epitope
C-Term
25
15
15
9
6
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
97
79
65
9
8
8
7
6
5
5
4
2
1
1
Host
Goat
77
16
16
Clonality
Polyclonal
Conjugate
This MYBL2 antibody is un-conjugated
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Western Blotting (WB)
76
43
33
26
14
10
5
3
2
2
1
1
1
1
Options
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Immunogen Peptide with sequence C-QEKARQLLGRLKPSH, from the C Terminus of the protein sequence
Specificity This antibody reacts to BMYB / MYBL2.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Human, Canine, Porcine, Bovine.
Species reactivity (tested):Rat.
Purification Affinity chromatography
Alternative Name MYBL2 (MYBL2 Antibody Abstract)
Background Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in the regulation of cell survival, proliferation, and differentiation. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes.Synonyms: B-Myb, BMYB, Myb-like protein 2, Myb-related protein B
Gene ID 4605
NCBI Accession NP_002457
UniProt P10244
Pathways Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding
Application Notes Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-MYBL2 antibody (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2) (C-Term) (ABIN374731) anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (C-Term) antibody
Background publications Shepard, Amatruda, Stern, Subramanian, Finkelstein, Ziai, Finley, Pfaff, Hersey, Zhou, Barut, Freedman, Lee, Spitsbergen, Neuberg, Weber, Golub, Glickman, Kutok, Aster, Zon: "A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13194-9, 2005 (PubMed).

Balagopalakrishna, Abugo, Horsky, Manoharan, Nagababu, Rifkind: "Superoxide produced in the heme pocket of the beta-chain of hemoglobin reacts with the beta-93 cysteine to produce a thiyl radical." in: Biochemistry, Vol. 37, Issue 38, pp. 13194-202, 1998 (PubMed).